DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and chil-26

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_001317724.1	Gene:	chil-26 / 188615	WormBaseID:	WBGene00011847	Length:	345	Species:	Caenorhabditis elegans

Alignment Length:	358	Identity:	70/358 - (19%)
Similarity:	125/358 - (34%)	Gaps:	117/358 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly  1938 THLIYGFAVLDSK-SLTIKTHDSWTDIDNRFYERVVEYKQRGLRVMLAIGGWNDSLGSKYARLVL 2001
            |:.::.||.|::. ||..::..|.....|  ..|..::....:..:|:|||.|.|  .|.:.::.
Worm    82 TYAVFAFAQLNTNGSLQFESAISKQKFLN--LNRKSKHINNNVNRILSIGGTNYS--EKLSIMLQ 142

  Fly  2002 NSQSRRRFVASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAFKENGL 2066
            :.:..|||:.|:|.||:.:..:|::|.|          ||.  ||:..:..|::.|
Worm   143 DLKKTRRFIMSIIRFLKDNELDGVELLW----------NRN--TEETLYCELLQHL--------- 186

  Fly  2067 ILSAAVSPSKMVIDAGYNVFELSPYFDWVAVMTYDFHGHWDMRTGQIAPLFHRGGDENLYLNGNF 2131
                     ||.::.....:.:|.......:      |.|           |.|.:
Worm   187 ---------KMGLEKQEKQYSISLRVPQTGI------GKW-----------HIGCE--------- 216

  Fly  2132 SIHYWLERGIPNDKLVMGMPMYGQTFTLADQ-NRRSLNDKTVGP------GKAGTFTRADGFLAY 2189
                                       |.|| |..|:|..::..      |..|....::.|...
Worm   217 ---------------------------LEDQENADSINLISMAEYENQLFGSGGVIRISEAFNTA 254

  Fly  2190 YEICEKVVNDDWK--------VVRDEEGIFGSYAYSGNQWISYDDVTTIRR-----KSQFIKSLQ 2241
            :|:.....|.:..        .:...|.|...|.::       .:...|:|     |:::.| ||
Worm   255 WEMKYHACNSNQSSKFNLVIPTIEQTEQIDMQYVWN-------PEKKEIQRFNSSTKTEYTK-LQ 311

  Fly  2242 LGGGMIWALDLDDFRGLCGCGKHPLLRTLSQEL 2274
            :||..||:.|: |:........:...|..||||
Worm   312 MGGVSIWSRDM-DYHNNIQLDSYFFERICSQEL 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753	64/335 (19%)
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351	68/356 (19%)
chil-26	NP_001317724.1	Glyco_18	82..323	CDD:214753	64/336 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810