DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and chil-22

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_496031.2	Gene:	chil-22 / 187738	WormBaseID:	WBGene00011166	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	419	Identity:	95/419 - (22%)
Similarity:	172/419 - (41%)	Gaps:	91/419 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1392 NHVLEEENIEATEMATE------FKIICYFTNWAWYRQGGGKFLPEDIDSDL-------CTHIIY 1443
            |:.:..||.|...|:.|      .|:|.||:              |...|::       .||.::
Worm    58 NYGVGRENREFQTMSEEDGEICDKKVIGYFS--------------ESHTSEITINHISKLTHAVF 108

  Fly  1444 GFAVLSRDNLTIQPHDSWADLDNKFYERIVAYR------KKGAKVTVAIGGWNDSAGDKYSRLVR 1502
            .|.::..|. |:...|..|.      ||.:..|      ....|:.::|||..:|  |.:..::.
Worm   109 AFVIMKSDG-TVMFRDKLAQ------ERFLKIRDIANQASPKLKMLISIGGPANS--DNFLPVIS 164

  Fly  1503 NPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAFQ--PR 1565
            :|:.:..||.:::.|:::|:.||:||.|::|          ..|:|..:|..:..|...||  .:
Worm   165 SPDRKKIFINSIVSFLKKYDIDGVDLFWKWP----------RLEDKYYYSRFISMLKERFQMEEK 219

  Fly  1566 GLILSAAVSP------NKKVIDAGYEVAELSHYFSWISVMAYDYHGQW----DKKTGHVAPMYSH 1620
            ..|||..:.|      |.|     :::..:.....:|::.:.||:|.|    ...||.::|:|:.
Worm   220 NYILSIIIPPCGFGGWNNK-----FDIENIVAVADFINIYSMDYYGPWKNPYGNPTGPISPIYNG 279

  Fly  1621 PEGTANFNANFSMNYWISMGADRRKLVMGIPLYGQSFSLAETTKHQLNAPTY------GGGEAGE 1679
            .:|...:|.:.|...:.......:|..:.||.:.:.:...|..........|      .|...||
Worm   280 AQGREAYNVHSSALTYSCKVKQSKKFNIVIPFFARLWKNVEKPIQHPGREVYRNVHLVHGSAVGE 344

  Fly  1680 ATRARGFLAYYEICLKIRHHRWNVVRDTKGRIGPFAYHG--DQWVSFDDVPMIRHKSEYIKAMGL 1742
            :..:|  .:..|...|:..:.:    |...| ..|.|:.  .::::|:....|..|..|:|...|
Worm   345 SFMSR--KSVLEKGYKLNSYSY----DELSR-SAFIYNSTTKEYLTFETEKSIEAKVNYVKDRAL 402

  Fly  1743 GGAMIWALDLDDFKNVCECESYPLLKAIN 1771
            .|..||.:||||.:|       .|:.|:|
Worm   403 AGVWIWFVDLDDEEN-------SLINAVN 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	82/375 (22%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	88/394 (22%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
chil-22	NP_496031.2	Glyco_18	82..413	CDD:214753	82/375 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164221
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740