DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and chil-18

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_496024.2	Gene:	chil-18 / 187735	WormBaseID:	WBGene00011161	Length:	429	Species:	Caenorhabditis elegans

Alignment Length:	402	Identity:	90/402 - (22%)
Similarity:	168/402 - (41%)	Gaps:	83/402 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1401 EATEMATEFKIICYFTNWAW---YRQGGGKFLPEDIDSDLCTHIIYGFAVLSRDNLTIQPHDSWA 1462
            :.|:...:.:::.|::.|..   .|...||.          ||.::.|..:          ||..
Worm    61 DLTKSPCKKRVVGYYSEWEGTEITRSQLGKL----------THAVFAFIHM----------DSEG 105

  Fly  1463 DLDNKF-----YERI---VAYRKKGAKVTVAIGGWNDSAGDKYSRLVRNPEARSRFIRNVLDFIE 1519
            .|..|.     :|::   |.......||.::|||  |...:.:..::.:.|.:|.||.::..||.
Worm   106 KLQFKTNQKERFEKLKTAVKNANSDTKVMISIGG--DHNSENFGSVLSDSEKKSMFIDSIARFIR 168

  Fly  1520 EYNFDGLDLDWEYPVCWQVDCKKGTAE-EKIGFSALVRELFYAFQP-RGLILSAAVSPNKKVIDA 1582
            ::...|:|:.|::         .|.:| |...|.:.:::|....:. |...:.:.|:|..| :|.
Worm   169 QHKIHGVDIYWKW---------LGNSETEHHDFPSFLKDLKEKLKTVRDDSIISIVAPQAK-MDR 223

  Fly  1583 ---GYEVAELSHYFSWISVMAYDYHG----QWDKKTGHVAPMYSHPEGTANFNANFSMNYWISMG 1640
               ||:..:...|..:::|.:.||:|    ||...||..||:|.......:||.:.:|.|:..|.
Worm   224 RHDGYKFDDFMEYIDFVNVFSMDYYGPWPNQWGTPTGPSAPLYGGIGVKKHFNVDSTMKYYTCMT 288

  Fly  1641 ADRRKLVMGIPLYGQSFSLAETTKHQLNAPT--------YGGGEAGEATRARGFLAY--YEICLK 1695
            .|..|..|.||.|   ..|.:..|..:::.|        ..|...|.:..:|..:.:  :|:...
Worm   289 EDPSKFNMVIPFY---VRLWKNVKEPISSGTEVFRRADLKNGAAVGNSYMSRWTVDHEGWELTPA 350

  Fly  1696 IRHHRWNVVRDTKGRIGPFAYHGD--QWVSFDDVPMIRHKSEYIKAMGLGGAMIWALDLDDFKNV 1758
            :    |:.|..|     |:.::.:  .:::|::...|..|..|.....|||..|..:|.|:
Worm   351 L----WDDVTKT-----PYVWNQETGNFLTFENKKSIEAKLAYAIEHNLGGVWIHLVDKDN---- 402

  Fly  1759 CECESYPLLKAI 1770
               |:..||:|:
Worm   403 ---ENEELLRAV 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	84/374 (22%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	89/392 (23%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
chil-18	NP_496024.2	Glyco_18	70..401	CDD:214753	84/374 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164226
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750