DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and chil-17

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_496019.1	Gene:	chil-17 / 187733	WormBaseID:	WBGene00011159	Length:	435	Species:	Caenorhabditis elegans

Alignment Length:	431	Identity:	85/431 - (19%)
Similarity:	179/431 - (41%)	Gaps:	84/431 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1392 NHVLEEENIEATEMATEFKIICYFTNWA-------WYRQGGGKFLPEDIDSD-LCTHIIYGF--- 1445
            |:.|..:.::...:.:...:.|...::|       :|::  .||...::..| :|...|.|:
Worm    22 NNELTTKLVKRVVIISGIFLFCGIVSYALTTFVFHFYKE--DKFSKNEVGLDPICKRRIVGYYSE 84

  Fly  1446 ---AVLSRDNLTIQPHDSWADLDNKF-----YERIVAYRK------------KGAKVTVAIGGWN 1490
               ..:|::.|....|..:|.:|.|:     ::.::..:|            ...|:..:|||
Worm    85 YDSTDISKNQLAKLTHAVFAFVDIKYDGTLQFKNLITEQKFFSLKSKARSLHSNLKLMFSIGG-- 147

  Fly  1491 DSAGDKYSRLVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALV 1555
            |.....:|..:.|.:.:|..|.:::.||..:..||:||.|::|          |:.:|..::.|:
Worm   148 DENSFDFSSALANTQMKSTLITSIIAFIHSHMIDGVDLHWKWP----------TSRDKSNYATLI 202

  Fly  1556 RELFYAFQ--PRGLILSAAVSP-NKKVIDAGYEVAELSHYFSWISVMAYDY----HGQWDKKTGH 1613
            ||:.....  ...:|:|..:.| .....::|:::..:..:..:|:|.:.||    ..||...||.
Worm   203 REIREKVDELDAKIIISITIPPVGVSDWESGFDLDAIQKHVDFINVHSMDYAKPLPNQWGTPTGP 267

  Fly  1614 VAPMYSHPEGTANFNANFSMNYWISMGADRRKLVMGIPLYGQSF-----SLAETTKHQLNAPTYG 1673
            .|.|..:.....::|.:::|.::.........:.:.||.|.:.:     ::...|:...|.....
Worm   268 SASMNFNIGLRQHYNVDWTMKHYTCELKKPSMINLVIPFYVRMWKNVQKAIDNRTEVFRNVELKD 332

  Fly  1674 GGEAGEATRARGFLAYYEICLKIRHHRWN------VVRDTKGRIGPFAYHGDQWVSFDDVPMIRH 1732
            ....|.:..:|..:.:.:  :::....|:      .|.|.|.|         .:.::::...|:.
Worm   333 NEVEGRSQLSRYTVEHED--MELSPESWDNATQTPYVLDLKTR---------TFFTYENEKSIKV 386

  Fly  1733 KSEYIKAMGLGGAMIWALDLDD---------FKNVCECESY 1764
            |.:|:..|.|||..||::|:||         |.|.. |.||
Worm   387 KLDYVNKMDLGGVWIWSVDMDDRLNTLLSFVFPNEL-CSSY 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	76/391 (19%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	83/412 (20%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
chil-17	NP_496019.1	Glyco_18	77..407	CDD:214753	69/352 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164223
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740