DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht10 and chil-15

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_496021.1	Gene:	chil-15 / 187731	WormBaseID:	WBGene00011157	Length:	432	Species:	Caenorhabditis elegans

Alignment Length:	363	Identity:	89/363 - (24%)
Similarity:	154/363 - (42%)	Gaps:	75/363 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1439 THIIYGFAVLSRDNLTIQPHDSWADLDNKFYERIVAYRKKG----AKVTVAIGGWNDSAGDKYSR 1499
            ||.|:.|..|..|. |:|.....|.      :|.:..:...    .||.::|||.:  ....:|.
Worm    98 THAIFAFIKLQPDG-TLQFQSGSAK------QRFLILKTNAESSTLKVMISIGGMD--INSDFSL 153

  Fly  1500 LVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQVDCKKGTAEEKIGFSALVRELFYAF-- 1562
            ::.:.:.|...|.:::.|:.|:..||:|:.|::          .::.:|..||..:|:|....
Worm   154 VISDEKKRRSLIESIVSFLTEHQIDGVDIFWKW----------SSSRDKFNFSVFMRDLREKLDK 208

  Fly  1563 QPRGLILSAAVSP-NKKVIDAGYEVAELSHYFSWISVMAYDYHGQWDKK----TGHVAPMYSHPE 1622
            |.:..|:|..:.| ...:.:.||::.|:..:..:::|.:.||.|.||.|    ||..|||..:..
Worm   209 QLKSYIVSILLPPAGVDIWEMGYDLDEIIDHIDFMNVYSMDYSGPWDNKWGTPTGPSAPMNYNIG 273

  Fly  1623 GTANFNANFSMNYWISMGADRRKLVMGIPLYG---QSFSLAETTKHQL--NAPTYGGGEAGEATR 1682
            ...:|..:::|.|:........|..:.||.|.   :|...|.|.|.::  ||....|...|:...
Worm   274 PRKHFTVDWTMKYYACKTRQPNKFNIVIPFYARIWRSVGEAITLKTEVFRNAKLINGKADGDPYI 338

  Fly  1683 ARGFLAYYEICLKIRHHRWNVVRDTKGRIGPFAYHGDQ-------W-------VSFDDVPMIRHK 1733
            :|         |.::.         || |..|.|..|.       |       ::|::...|..|
Worm   339 SR---------LSVKQ---------KG-IELFPYSWDNATKSSYIWKPKEKTFLTFENERSIEKK 384

  Fly  1734 SEYIKAMGLGGAMIWALDLDDFKNVCECESYPLLKAIN 1771
            .:|:..|.|||..||::|:||..|.       ||.|::
Worm   385 LQYVNEMNLGGVWIWSVDMDDRINT-------LLDAVS 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753	83/343 (24%)
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351	89/363 (25%)
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
chil-15	NP_496021.1	Glyco_18	76..404	CDD:214753	83/343 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164224
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740