DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht10 and chil-12

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_506770.2	Gene:	chil-12 / 187357	WormBaseID:	WBGene00010799	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	411	Identity:	94/411 - (22%)
Similarity:	170/411 - (41%)	Gaps:	103/411 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1902 PIINNSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLIYGF--AVLDSKSLTIK-----THDS 1959
            ||....|..:....:.:.|.|.:.||.|...:.|.|:..|.|:  ...||: :||.     ||..
Worm    56 PITKAGYTPLSSPDASSIYNSFKNKFPPIKTEENTCSKRIIGYYSGTSDSE-ITINQVSKLTHAI 119

  Fly  1960 WTDID------------NRF--YERVVEYKQRGLRVMLAIGGWNDSLGSKYARLVLNSQSRRRFV 2010
            :..:.            |||  ...:.:.:...::.|.:|||...|  ..::.:|.|.:.:|||:
Worm   120 FAFVQLTFDGTLVFRNKNRFMALRNIAKTENSTVKFMFSIGGPGHS--QNFSPVVRNQEKKRRFI 182

  Fly  2011 ASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEAFK-ENGLILSAAVSP 2074
            .|:.||||:|..:|:|:.|::|          :..:|..:...:.||:|..| ....|||..|.|
Worm   183 KSIFSFLEEHKLDGVDIFWKWP----------HLADKHAYSQFLLELNEILKTRKDYILSILVPP 237

  Fly  2075 SKMVIDAGYNVFELSPYFDWVAVMTYDFHG----HWDMRTGQIAPLFHRGGDE-----NLYLNGN 2130
            ..:...:|:.:.|:....|::.:...|::|    .|...||.|:|::  ||.|     |:   .|
Worm   238 QGIGFASGFKMNEIVENVDFINIFAMDYYGPWASGWGNPTGPISPIY--GGSERREQWNV---DN 297

  Fly  2131 FSIHYWLERGIPNDKLVMGMPMYGQTFTLADQNRRSLNDKTVG-----PGKAGTFTRADGFLAYY 2190
            .:..|..|. :.:.|..:.:|.:.:.:            ..||     |||
Worm   298 TAAIYSCET-MRSSKFNIVIPFFARLW------------NNVGKPIDFPGK-------------- 335

  Fly  2191 EICEKVVNDDWKVVRD---------EEGI-FGSYAY------------SGNQWISYDDVTTIRRK 2233
            |:...|...|.|.|.:         ::|. ..||.|            :..::::::...:|..|
Worm   336 EVYRNVTLIDGKAVGEVYMPRRSALQKGYNLSSYNYDDLSETAFIYNSTTKEYLTFEVKRSIAAK 400

  Fly  2234 SQFIKSLQLGGGMIWALDLDD 2254
            ..:::::.|||..||.:|:||
Worm   401 LDYVQNMNLGGVWIWQMDMDD 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753	89/401 (22%)
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351	91/403 (23%)
chil-12	NP_506770.2	Glyco_18	94..420	CDD:214753	82/370 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164220
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.750