DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and chil-8

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_001379090.1	Gene:	chil-8 / 174541	WormBaseID:	WBGene00007473	Length:	399	Species:	Caenorhabditis elegans

Alignment Length:	409	Identity:	97/409 - (23%)
Similarity:	177/409 - (43%)	Gaps:	83/409 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   219 KKVLCYMSNWAFYRSGE-AHFVPEQIDPNLCSAIIYSFASLDPDHLTIR----EFDSWVDLDNQY 278
            |:::.|:|      |.| :....:|::.  .:.:|::|..:..|. ||:    ..|.:.|:.
Worm    48 KRIIGYVS------SDEGSEITIKQLEK--LTHVIFAFILVHKDG-TIKFKYGTKDGFFDMK--- 100

  Fly   279 YRRVTSL--GVPVLIALGGWTDSSGSKYSRLVSDNL--KRRVFISSVSSFLLRHGFSGLHLDWNY 339
             |:...|  |:.|::::||:..|.      |.||.|  |::..|:|::..:.:....|:.:.||:
Worm   101 -RKSMELNRGLKVMVSIGGYESSP------LFSDVLVKKKKKLIASIALLVKKFDLDGVDIFWNW 158

  Fly   340 PKCWQSDCSRGPVTDRPNLTKLLRELRTEFQSV------DPKFQLGVAISGYKEIIKEAYDFPAL 398
            |.          :||:.|....:||||.:..::      ..::.:.|.........:..|.:..:
Worm   159 PS----------ITDQSNYLIFIRELRKKLTNLKDENGRSNEYVISVIAPSSSSHSEYPYKWTEI 213

  Fly   399 SDIVDYMTVMTYDYHGAWE-QKTGHVSPLYGLSSDTYPQYNTNYTMQLLLKMGARREKLVLSIPF 462
            .:.||::.|:|::|.  :| .|.|..|||||.|..     |.:.|::.|:.......||.:.:.|
Worm   214 LENVDFINVITFEYF--YEANKIGPHSPLYGGSFG-----NVDDTLKYLICRTRTPNKLNMVVSF 271

  Fly   463 ---YGQSFTLATAHQILAGPGVAASGPGDAGELTKQPGMLAY------YEICQRL-TKFNWISDR 517
               |..:.||....:.:..|..:|.||...|  .||...:::      :|..:.. |.:.|.:|
Worm   272 NGIYWGNTTLPFDDKGVWIPDDSAQGPYSYG--WKQFARMSHGFDQNDFEWNEETRTPYIWKAD- 333

  Fly   518 NLNVIFGPFAMLNDQWVGYEDPTSAQAKARYAANNNFAGVAAWTIDLDDFRNLCCNESYPLLRAI 582
                        ..|::.:|:..|...|..||..:|..|||.:|||.||..|...|.....|.::
Worm   334 ------------TQQFLTFENEKSLTEKMNYAVAHNIGGVAMYTIDDDDEENTLLNVVVTNLPSL 386

  Fly   583 NRALGRLDSEPPTQPNCKR 601
            .::.|.      |:.||.|
Worm   387 KKSGGE------TKYNCTR 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753	86/370 (23%)
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351	91/390 (23%)
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
chil-8	NP_001379090.1	Glyco_18	49..369	CDD:214753	86/370 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164206
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740