DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht10 and chil-21

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_496029.2	Gene:	chil-21 / 174502	WormBaseID:	WBGene00011164	Length:	470	Species:	Caenorhabditis elegans

Alignment Length:	437	Identity:	103/437 - (23%)
Similarity:	179/437 - (40%)	Gaps:	92/437 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly  1876 SSLGSNQRTQEPAVHRPNPTSVITEPPIINNSYKVV--CYFTSWAWYRSSQGKFVPEDIDANLCT 1938
            ||.|:.............||.......:..::|...  |......:|.::|...:..|..:.| |
Worm    69 SSAGTRSTFASGFFSECTPTVTSISSTVAASTYPATPGCNKRIIGYYFATQTSVITRDQVSKL-T 132

  Fly  1939 HLIYGFAVLDSKSLTIKTHDSWTDID-----NRFYERVVEYKQR--GLRVMLAIGGWNDSLGSKY 1996
            |.::.|..:        |.|....||     |||...:...||:  .::||::||| ||:  |..
Worm   133 HAVFAFVNM--------TSDGHLQIDGDLAKNRFTNLIEIAKQQTPQVKVMISIGG-NDN--SNN 186

  Fly  1997 ARLVLNSQSRRR-FVASVISFLEQHGFEGLDLAWEFPVCWQVNCNRGNPTEKDGFVALVKELSEA 2060
            .:.||:|..|:: |:.|.:|||:.:..:|:||.|::|          ..|.||.:...:.:|..:
Worm   187 FKPVLSSPDRKKLFINSTVSFLQTYDIDGVDLYWKWP----------GKTSKDIYSQFINDLRYS 241

  Fly  2061 F--KENGLILSAAVSPSKM--VIDAGYNVFELSPYFDWVAVMTYDFHGHWD----MRTGQIAPLF 2117
            .  ::...|:|..:.|..|  ..:||.::..:....|::.:.|..:.|.|.    |.||..:.||
Worm   242 LQRQKRNYIMSIVLPPPDMGANYEAGIDIENIFDNVDFLNIFTMGYFGPWQNDAGMITGAASQLF 306

  Fly  2118 HRGGDENLYLNG-----NFSIHYWLERGI----PNDKLVMGMPMYGQTFTLADQNRRSLNDKTVG 2173
            :.       :||     .::||:..||.:    .:||..:.:|.|..   |....:..:|...:.
Worm   307 NG-------VNGVPGRKTYNIHHSTERYVCKTGQSDKYNIAIPFYTM---LWKHVKGPVNPPNIE 361

  Fly  2174 PGKAGTFTRADGFLAYYEICEKVVNDDWKVVRDEEG-----------IFGSYAYSG--NQWISYD 2225
            ..:..||  ..|.:....:..|:|        .|||           |..::.|:.  ..:::::
Worm   362 IYRNATF--QGGVVGETSMSRKLV--------QEEGYDFSNPTYNPEIRAAFKYNATTETFLTFE 416

  Fly  2226 DVTTIRRKSQFIKSLQLGGGMIWALDLDD----------FRGLCGCG 2262
            ...||..|..::|...|||..|||:|:||          |.|.|..|
Worm   417 TNDTIAAKIDYVKDRILGGVWIWAVDMDDDSNNLLNLVKFTGYCTVG 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753	91/383 (24%)
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351	97/403 (24%)
chil-21	NP_496029.2	Glyco_18	110..444	CDD:214753	90/375 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164214
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740