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Protein Alignment Cht10 and CHIT1

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_003456.1	Gene:	CHIT1 / 1118	HGNCID:	1936	Length:	466	Species:	Homo sapiens

Alignment Length:	482	Identity:	173/482 - (35%)
Similarity:	254/482 - (52%)	Gaps:	60/482 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1410 KIICYFTNWAWYRQGGGKFLPEDIDSDLCTHIIYGFAVLSRDNLTIQPHDSWADLDNKFYERIVA 1474
            |::|||||||.||||..:|||:|:|..||||:||.||.::...|:.   ..|.  |...|:....
Human    23 KLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTNHQLST---TEWN--DETLYQEFNG 82

  Fly  1475 YRKKGAKV--TVAIGGWNDSAGDKYSRLVRNPEARSRFIRNVLDFIEEYNFDGLDLDWEYPVCWQ 1537
            .:|...|:  .:||||||... .|::.:|.....|..|:.:.:.|:.:|:|||||||||||
Human    83 LKKMNPKLKTLLAIGGWNFGT-QKFTDMVATANNRQTFVNSAIRFLRKYSFDGLDLDWEYP---- 142

  Fly  1538 VDCKKGTAEEKIGFSALVRELFYAFQPRG-------LILSAAVSPNKKVIDAGYEVAELSHYFSW 1595
             ..:...|.:|..|:.||::|..|||...       |:|||||...:..:||||||.:::....:
Human   143 -GSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAVPAGQTYVDAGYEVDKIAQNLDF 206

  Fly  1596 ISVMAYDYHGQWDKKTGHVAPMYSHPE---GTANFNANFSMNYWISMGADRRKLVMGIPLYGQSF 1657
            :::||||:||.|:|.|||.:|:|...|   ..|:.|.:.::..|:..|....||::|:|.||:||
Human   207 VNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSF 271

  Fly  1658 SLAETTKHQLNAPTYGGGEAGEATRARGFLAYYEICLKIRHHRWNVVRDTKGRIG----PFAYHG 1718
            :||.::..::.||..|.|..|..|:..|.|||||:|      .|...  ||.||.    |:.:..
Human   272 TLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVC------SWKGA--TKQRIQDQKVPYIFRD 328

  Fly  1719 DQWVSFDDVPMIRHKSEYIKAMGLGGAMIWALDLDDFKNV-CECESYPLLKAINRVLRGFGGPQP 1782
            :|||.||||...:.|..|:|..||||||:||||||||... |....|||::.:.:.|
Human   329 NQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRYPLIQTLRQEL-------- 385

  Fly  1783 KCLLENPKSTMKPNIKPPFRPTINAPSGPNLDSPTQNVSLNVLSIKCHSK--NYLAHEWDCTKYY 1845
             .|...|..|.:..:..|.:|: ....||   ||.|:..       |..|  ....:..:.:.:|
Human   386 -SLPYLPSGTPELEVPKPGQPS-EPEHGP---SPGQDTF-------CQGKADGLYPNPRERSSFY 438

  Fly  1846 ICEHGTYVERSCPLGLQWNKT--YCDW 1870
            .|..|...::|||.||.::.:  .|.|
Human   439 SCAAGRLFQQSCPTGLVFSNSCKCCTW 465

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.