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Protein Alignment Cht10 and CHI3L2

DIOPT Version :9

Sequence 1:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster
Sequence 2:	NP_003991.2	Gene:	CHI3L2 / 1117	HGNCID:	1933	Length:	390	Species:	Homo sapiens

Alignment Length:	384	Identity:	145/384 - (37%)
Similarity:	229/384 - (59%)	Gaps:	36/384 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly  1906 NSYKVVCYFTSWAWYRSSQGKFVPEDIDANLCTHLIYGFAVLDSKSLTIKTHDSWTDIDNRFYER 1970
            ::||:|||||:|:..|...|||.||:||..||:||||.||.:::..:.||...     :...|:.
Human    25 SAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKS-----EVMLYQT 84

  Fly  1971 VVEYKQRG--LRVMLAIGGWNDSLGSK-YARLVLNSQSRRRFVASVISFLEQHGFEGLDLAWEFP 2032
            :...|.:.  |:::|:|||:  ..||| :..:|.:|.||..|:.|:|.||..|.|:|||::|.:|
Human    85 INSLKTKNPKLKILLSIGGY--LFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYP 147

  Fly  2033 VCWQVNCNRGNPTEKDGFVALVKELSEAFKEN-------GLILSAAVSPSKMVIDAGYNVFELSP 2090
                      :..|...|..|:.||:|||:::       .|:|:|.||..:.:||..|.|.:|:.
Human   148 ----------DQKENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQMIDNSYQVEKLAK 202

  Fly  2091 YFDWVAVMTYDFHGHWD--MRTGQIAPLFHRGGDE--NLYLNGNFSIHYWLERGIPNDKLVMGMP 2151
            ..|::.::::||||.|:  :.||..:||.....|.  :.|.|..:::.||:.:|:|::|:|||:|
Human   203 DLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIP 267

  Fly  2152 MYGQTFTLADQNRRSLNDKTVGPGKAGTFTRADGFLAYYEICEKVVNDDWKVVRDEEGIFGSYAY 2216
            .||.:||||.. ..::.....|||.||..|.:.|||||||||:.:.......::|::   ..||.
Human   268 TYGHSFTLASA-ETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKITRLQDQQ---VPYAV 328

  Fly  2217 SGNQWISYDDVTTIRRKSQFIKSLQLGGGMIWALDLDDFRG-LCGCGKHPLLRTLSQEL 2274
            .||||:.||||.::..|.||:|:|.|||.|||::|:|||.| .|..|.:||::.:.:.|
Human   329 KGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSL 387

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.