Protein Alignment Spf45 and RBM17

DIOPT Version :9

• Sequence 1: NP_001036426.1
• Gene: Spf45 / 3355114
• FlyBaseID: FBgn0086683
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_001139019.1
• Gene: RBM17 / 84991
• HGNCID: 16944
• Length: 401
• Species: Homo sapiens
• Alignment Length: 456
• Identity: 161/456 - (35%)
• Similarity: 219/456 - (48%)
• Gaps: 113/456 - (24%)

  Fly     1 MDLYDGIDTRARSSQIDGWSSGIKMLQTQLAVKMAV----------KKPLMTPVVNLRSKRLADP 55
            |.|||.:......|:.:|||...|:||:||.||.|.          :..::.||::|:....:|.
Human     1 MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQRTKQSTVLAPVIDLKRGGSSDD 65

  Fly    56 EVTCFAP--ITTVVSKPLISGKALPSILERINRGDWDVADEYDPQRPNEYEKLKEKSNGSDKNRA 118
            ......|  :...:..|:.||.:...:|       ..:||||||..||:|||:.::.....:.:.
Human    66 RQIVDTPPHVAAGLKDPVPSGFSAGEVL-------IPLADEYDPMFPNDYEKVVKRQREERQRQR 123

  Fly   119 GVSDREDRDDKEKDRKRGRVGRREFYRDEVSAPNLKLSGFGHR---QNDDDMYLPSPGLVAKQGG 180
            .:..:::.:::||.||    .|.|            .|||..|   .:|:|............||
Human   124 ELERQKEIEEREKRRK----DRHE------------ASGFARRPDPDSDEDEDYERERRKRSMGG 172

  Fly   181 ATIAPPPSLQEMSIDSGCEATNTMPYSASS----------------------------------- 210
            |.||||.||    ::...|.....||...|
Human   173 AAIAPPTSL----VEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEQDRPRSPTGPSNSFLAN 233

  Fly   211 ----VAAKIMAKYGFKDGQGLGKSEQGMAIALQVEKTSKRGGRIIHEKDVFLPPLALSPPSIGSQ 271
                ||.|||.||||::||||||.|||::.||.|||||||||:||                :|..
Human   234 MGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGKII----------------VGDA 282

  Fly   272 IGTSPSHKAMPPPQMVDTAAESGDIGYSITEIMKSPSKVVLLRNMVGPGDVDEELEPEVKDECNT 336
            .....|.|:...|               :|||:|.|:||||||||||.|:|||:||.|.|:||.
Human   283 TEKDASKKSDSNP---------------LTEILKCPTKVVLLRNMVGAGEVDEDLEVETKEECE- 331

  Fly   337 KYGEVNSVIIHESFGTVPEDAVKIFVEFRRIESAIKAVVDLNGRFFGGRQVRAGFYNYDKFKCFQ 401
            |||:|...:|.|..|...::||:||:||.|:|||||||||||||:||||.|:|.|||.|||:...
Human   332 KYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLD 396

  Fly   402 L 402
            |
Human   397 L 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spf45	NP_001036426.1	G-patch	209..248	CDD:279867	28/77 (36%)
		RRM_UHM_SPF45	307..402	CDD:241091	60/94 (64%)
RBM17	NP_001139019.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	57..84		4/26 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..233		25/138 (18%)
		G-patch	235..279	CDD:396249	31/59 (53%)
		RRM_UHM_SPF45	303..397	CDD:410051	60/94 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147649
Domainoid	1	1.000	74	1.000	Domainoid score	I9210
eggNOG	1	0.900	-	-		E1_KOG1996
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13162
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3489
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60100
OrthoDB	1	1.010	-	-		D1101846at2759
OrthoFinder	1	1.000	-	-		FOG0005833
OrthoInspector	1	1.000	-	-		oto89643
orthoMCL	1	0.900	-	-		OOG6_103640
Panther	1	1.100	-	-	LDO	PTHR13288
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3833
SonicParanoid	1	1.000	-	-		X4816
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800