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Protein Alignment Spf45 and SCN10A

DIOPT Version :9

Sequence 1:	NP_001036426.1	Gene:	Spf45 / 3355114	FlyBaseID:	FBgn0086683	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	XP_005265428.1	Gene:	SCN10A / 6336	HGNCID:	10582	Length:	1959	Species:	Homo sapiens

Alignment Length:	221	Identity:	46/221 - (20%)
Similarity:	70/221 - (31%)	Gaps:	75/221 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 FYRDEVSAP-------NL-----KLSGFGHRQNDDDMYLPSPGLVAKQGGATIAPPPSLQEMSID 195
            |..|.::||       ||     ::..||||...        .|.:....:...|.|..:.
Human   896 FSADNLTAPEDDGEVNNLQVALARIQVFGHRTKQ--------ALCSFFSRSCPFPQPKAEP---- 948

  Fly   196 SGCEATNTMPYSASSVAAKIMAKYGFKDGQGLGKSEQGMAIALQVEKTSKRGGRIIHEKDVFLPP 260
               |....:|.|:|.....|.|           .:.:|.:..||    :.||.|..|...:..|.
Human   949 ---ELVVKLPLSSSKAENHIAA-----------NTARGSSGGLQ----APRGPRDEHSDFIANPT 995

  Fly   261 LALSPP------------SIGSQIGTSPSHKAMPPPQ--MVDTAAESGDIGYSITEIMKSPSKVV 311
            :.:|.|            ..|.:...|...:.:|..|  .:......||   .:|.  :||
Human   996 VWVSVPIAEGESDLDDLEDDGGEDAQSFQQEVIPKGQQEQLQQVERCGD---HLTP--RSP---- 1051

  Fly   312 LLRNMVGPGDVDEELEPEV----KDE 333
                  |.|...|:|.|.:    |||
Human  1052 ------GTGTSSEDLAPSLGETWKDE 1071

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.