Protein Alignment Spf45 and PTGS2

DIOPT Version :9

• Sequence 1: NP_001036426.1
• Gene: Spf45 / 3355114
• FlyBaseID: FBgn0086683
• Length: 403
• Species: Drosophila melanogaster
• Sequence 2: NP_000954.1
• Gene: PTGS2 / 5743
• HGNCID: 9605
• Length: 604
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 39/198 - (19%)
• Similarity: 66/198 - (33%)
• Gaps: 76/198 - (38%)

  Fly   173 GLVAKQGGATIAPPPSLQEMSIDSGCEATNTMPYSA----------------------SSVAAKI 215
            |.||  ||..:  ||::|::| .:..:.:..|.|.:                      ..::|::
Human   418 GRVA--GGRNV--PPAVQKVS-QASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAEL 477

  Fly   216 MAKYGFKDGQGLGKSEQGMAIALQVEKTSKRGGRIIHEK---------------DVFLPPLALSP 265
            .|.||..|...|..       ||.|||  .|...|..|.               :|...|....|
Human   478 EALYGDIDAVELYP-------ALLVEK--PRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKP 533

  Fly   266 PSIGSQIGTSPSHKA-------------------MPPPQMVDT------AAESGDIGYSITEIMK 305
            .:.|.::|....:.|                   :|.|:::.|      ::.||....:.|.::|
Human   534 STFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLK 598

  Fly   306 SPS 308
            ..|
Human   599 ERS 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spf45	NP_001036426.1	G-patch	209..248	CDD:279867	12/38 (32%)
		RRM_UHM_SPF45	307..402	CDD:241091	1/2 (50%)
PTGS2	NP_000954.1	EGF_CA	19..54	CDD:238011
		prostaglandin_endoperoxide_synthase	75..562	CDD:188648	31/157 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.78878	Normalized mean entropy	S3904
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950