DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spf45 and hpx-2

DIOPT Version :9

Sequence 1:	NP_001036426.1	Gene:	Spf45 / 3355114	FlyBaseID:	FBgn0086683	Length:	403	Species:	Drosophila melanogaster
Sequence 2:	NP_506432.1	Gene:	hpx-2 / 179880	WormBaseID:	WBGene00008627	Length:	718	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	41/188 - (21%)
Similarity:	68/188 - (36%)	Gaps:	65/188 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 RSKRLAD-----PEVTCFAPITTVVSKPLISGKALPSILERINRGDWDVADEYDPQR-------- 99
            ||||.|:     |.:.|.....|.:..  |:|..       .||.:.|:.:...|.|
Worm   133 RSKRQANRRCSSPPINCNNRFHTSIRS--ITGLC-------NNRQNSDLGNSVSPLRRILGAASY 188

  Fly   100 PNEYEKLKEKS-NGSDKNRAGVSDREDRDDKEKDRKRGRVGRREFYRDEVSAPNLK----LSG-- 157
            .:...:::.:| ||.:...|.:......||:               .::|.:|::.    :.|
Worm   189 ADGLGRIRTRSVNGGELPSARLISNRIHDDR---------------NNQVFSPSINHLHMIIGQF 238

  Fly   158 FGHRQNDDDMYLPSPGLVAKQGGATIAPPPSLQEMSIDSGCEATNTMPYSASSVAAKI 215
            ..|    |.:::||.  ||:.|||            :|  |.|.|: |...|...|.|
Worm   239 IAH----DVVFMPSS--VARDGGA------------LD--CSACNS-PQRVSPNCAPI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spf45	NP_001036426.1	G-patch	209..248	CDD:279867	3/7 (43%)
Spf45	NP_001036426.1	RRM_UHM_SPF45	307..402	CDD:241091
hpx-2	NP_506432.1	An_peroxidase	158..696	CDD:376988	33/163 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.78878	Normalized mean entropy	S3904
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950