DRSC/TRiP Functional Genomics Resources

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Protein Alignment FASN3 and NQR

DIOPT Version :10

Sequence 1:NP_001015405.3 Gene:FASN3 / 3355111 FlyBaseID:FBgn0287184 Length:2394 Species:Drosophila melanogaster
Sequence 2:NP_001185182.1 Gene:NQR / 841391 AraportID:AT1G49670 Length:652 Species:Arabidopsis thaliana


Alignment Length:361 Identity:80/361 - (22%)
Similarity:140/361 - (38%) Gaps:74/361 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly  1432 LKGPFNSQNCHIKIAFSSLNFRDVMLATGRLAVELYGSSRIDQNCVLGFEYSGINMLTGRRIMSM 1496
            |:.|.......:||.::.:|..||..::||....  ||.::..:.  |||..|:....|..:.::
plant   310 LQLPIGPHQVLLKIIYAGVNASDVNFSSGRYFTG--GSPKLPFDA--GFEGVGLIAAVGESVKNL 370

  Fly  1497 VVK--------GGVASYVEKPSKLIWDIPDD-----WSLEEAATVPVVYITVY------------ 1536
            .|.        |..:.|:...||.:..:|..     ..|....|..:....:|            
plant   371 EVGTPAAVMTFGAYSEYMIVSSKHVLPVPRPDPEVVAMLTSGLTALIALEKLYDILKLLVQLSLT 435

  Fly  1537 ----YAFFMATDIRKGKSILIHAGTGGIGLAAIRVALAYNLEVFTTCSTANKKEFLLKTFPKLKE 1597
                |....|..::.|:::|:.|..||.|..|:::|.....:|..||..:.|.: |||   :|..
plant   436 FSLSYGNSQAGQMKSGETVLVTAAAGGTGQFAVQLAKLSGNKVIATCGGSEKAK-LLK---ELGV 496

  Fly  1598 SHIGNSRNTSFELMVHRETNGKGVDFVLNSLSEEKLLASLRCLGKSGHFLEIGKYDMANDNK--- 1659
            ..:.:.::.:.:.::.:|. .|||:.:..|:..:.....|..|...|..:.||........|   
plant   497 DRVIDYKSENIKTVLKKEF-PKGVNIIYESVGGQMFDMCLNALAVYGRLIVIGMISQYQGEKGWE 560

  Fly  1660 ----IGLGCFLKEITFHAVLADSLLVA-----PDEDIW--HLKSLIDM----DISNGIIQPLPVK 1709
                .|| |       ..:||.|..||     ....:|  :|..|.::    .:..||.|    |
plant   561 PAKYPGL-C-------EKILAKSQTVAGFFLVQYSQLWKQNLDKLFNLYALGKLKVGIDQ----K 613

  Fly  1710 VFLA-HEIEQAFRHLIGGKHIGKVVIQVREQPHDPS 1744
            .|:. :.:..|..:|..||..||||:.:     ||:
plant   614 KFIGLNAVADAVEYLHSGKSTGKVVVCI-----DPA 644

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FASN3NP_001015405.3 PksD 16..>839 CDD:442550
hot_dog 877..1125 CDD:469797
Rossmann-fold NAD(P)(+)-binding proteins <1301..>1411 CDD:473865
PKS_ER 1443..1734 CDD:214840 75/338 (22%)
KR_1_FAS_SDR_x <1761..1988 CDD:187657
PKS_PP 2000..2067 CDD:214834
alpha/beta hydrolases 2120..>2265 CDD:473884
NQRNP_001185182.1 ADH_SDR_c_like 9..254 CDD:187584
Mgc45594_like 286..640 CDD:176212 78/350 (22%)
Blue background indicates that the domain is not in the aligned region.

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