DRSC/TRiP Functional Genomics Resources

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Protein Alignment FASN3 and adh8

DIOPT Version :10

Sequence 1:NP_001015405.3 Gene:FASN3 / 3355111 FlyBaseID:FBgn0287184 Length:2394 Species:Drosophila melanogaster
Sequence 2:NP_595121.1 Gene:adh8 / 2540139 PomBaseID:SPBC1773.06C Length:346 Species:Schizosaccharomyces pombe


Alignment Length:342 Identity:84/342 - (24%)
Similarity:139/342 - (40%) Gaps:79/342 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly  1443 IKIAFSSLNFRDVMLATGRLAVELY--------GSSRIDQ--NCVLGFE---------------- 1481
            :|:..:|||:||:::..|...:.|.        |:..|::  ..|.|||                
pombe    35 VKLKAASLNYRDLIITKGLYPLPLQLPVVPGSDGAGIIEKVGEDVEGFEKGDSVVCNFFTNYLDG 99

  Fly  1482 ----YSGINMLTGRRIMSMVVKGGVASYVEKPSKLIWDIPDDWSLEEAATVPVVYITVYYAFFMA 1542
                ::..:.|.|.|      .|....|...|:..:...|.:.|.||.||:|...:|.:...|.:
pombe   100 TPTDFATHSALGGTR------DGCFQKYAVLPAHALVHAPKNLSFEEIATLPCAAVTAWNGLFGS 158

  Fly  1543 TD--IRKGKSILIHAGTGGIGLAAIRVALAYNLEVFTTCSTANKKEFLLKTFPKLKESHIGNSRN 1605
            .:  ::.|.::|: .||||:...|::.|||....|..|.|:..|.||.    .||..:|..|.:.
pombe   159 KEHQVKPGNNVLV-LGTGGVSTFALQFALAAGANVTVTSSSDEKLEFA----KKLGATHTINYKK 218

  Fly  1606 T-SFELMVHRETNGKGVDFVLNSLSEEKLLASLRCLGKSGHFLEIGKY--------------DMA 1655
            | .:.....:.|||.|...|:....|:.|..|:.||.|.|....||..              .:.
pombe   219 TPQWASPALKMTNGVGYHHVIEVGGEKTLPQSIACLAKDGMISMIGFVASEGTTPNLTSIIGQIL 283

  Fly  1656 NDNKIGLGCFLKEIT-FHAVLADSLLVAPDEDIWHLKSLIDMDISNGIIQPLPVKVFLAHEIEQA 1719
            |.|....|.|:..:: |..::|  .:.|.|                  |.|:..|||...::::|
pombe   284 NRNANIRGIFVGSVSMFRDMVA--CIEAKD------------------IHPVVDKVFPFDQLKEA 328

  Fly  1720 FRHLIGGKHIGKVVIQV 1736
            :.:.....||||||:::
pombe   329 YEYQWSQAHIGKVVLKI 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
FASN3NP_001015405.3 PksD 16..>839 CDD:442550
hot_dog 877..1125 CDD:469797
Rossmann-fold NAD(P)(+)-binding proteins <1301..>1411 CDD:473865
PKS_ER 1443..1734 CDD:214840 83/338 (25%)
KR_1_FAS_SDR_x <1761..1988 CDD:187657
PKS_PP 2000..2067 CDD:214834
alpha/beta hydrolases 2120..>2265 CDD:473884
adh8NP_595121.1 MDR7 12..345 CDD:176237 84/340 (25%)
Blue background indicates that the domain is not in the aligned region.

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