DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Parp and AT5G22470

DIOPT Version :9

Sequence 1:	NP_001104452.1	Gene:	Parp / 3355109	FlyBaseID:	FBgn0010247	Length:	994	Species:	Drosophila melanogaster
Sequence 2:	NP_001318618.1	Gene:	AT5G22470 / 832308	AraportID:	AT5G22470	Length:	815	Species:	Arabidopsis thaliana

Alignment Length:	861	Identity:	212/861 - (24%)
Similarity:	377/861 - (43%)	Gaps:	122/861 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 LADDDQAKVKNAIPPIKSE-ELPDTKRAKMELSDTNEEGEKKQRLKDQNDAYFRFRDDIKNKMKK 247
            ::.|:|.  |..:...|:| :||::::::.:....|::|.......|....|..|...::..:..
plant    12 MSGDEQK--KGNLRKHKAEGKLPESEQSQKKAKPENDDGRSVNGAGDAASEYNEFCKAVEENLSI 74

  Fly   248 KDIDILLKFNNQQPVTGDTEKLFDQTADLLTFGAIESCSECNSCQFIVNKSGYICNGNHSEWTKC 312
            ..|..:|:.|.|. .:...|.|..|..|||.:||:..|..|.......|:..::|.|..|||..|
plant    75 DQIKEVLEINGQD-CSAPEETLLAQCQDLLFYGALAKCPLCGGTLICDNEKRFVCGGEISEWCSC 138

  Fly   313 NKLLKEPTRSACIVPKELKALYNFLNTVKEIPSTRIFNNFPPNKSTFSRSLLKTNKNNDVLVRP- 376
            ....|:|.|      ||        ..|| ||.: :.|      |..| .|:|  |:.|...||
plant   139 VFSTKDPPR------KE--------EPVK-IPDS-VMN------SAIS-DLIK--KHQDPKSRPK 178

  Fly   377 -TIPRISPPLYNLKFSIIG-LKNQHKELRKRIENLGGKFEVKISENTIAIISTELEIQKKSTRMK 439
             .:.....|...:..|::| |...|:..:|:||..|||....:...|..::|.....:..:::|.
plant   179 RELGSADKPFVGMMISLMGRLTRTHQYWKKKIERNGGKVSNTVQGVTCLVVSPAERERGGTSKMV 243

  Fly   440 FAEELGIHIVP----IEFLDFVEADTEGAIKYINSTCICSWGTDPKSRIPKETT--------KSL 492
            .|.|.|:.:|.    |:.::..||....|...::...:...|.....:.|.|..        |..
plant   244 EAMEQGLPVVSEAWLIDSVEKHEAQPLEAYDVVSDLSVEGKGIPWDKQDPSEEAIESFSAELKMY 308

  Fly   493 NSNSIYTKSMPVSRTFKV--KDGLAVDPDSGLEDIAHVYVDSNNKYSVVLGLTDIQRNKNSYYKV 555
            ....:|..:....|..|:  ||||.                    |:....:.|:.:.:|.|..:
plant   309 GKRGVYMDTKLQERGGKIFEKDGLL--------------------YNCAFSICDLGKGRNEYCIM 353

  Fly   556 QLLKADKKEKYWIFRSWGRIGTN-IGNSKLEEFDTSESAKRNFKEIYADKTGNEYE--QRDNFV- 616
            ||:..........|:. |::|.: ....:|||::..|:|.:.|..::.:..|||:|  :|:..:
plant   354 QLVTVPDSNLNMYFKR-GKVGDDPNAEERLEEWEDEEAAIKEFARLFEEIAGNEFEPWEREKKIQ 417

  Fly   617 KRTGRMYPIEIQYDDD----------QKLVKHESHFFTSKLEISVQNLIKLIFDIDSMNKTLMEF 671
            |:..:.:||::  ||.          ::|....:|   .||:..|.|.||::...:..|..|||.
plant   418 KKPHKFFPIDM--DDGIEVRSGALGLRQLGIASAH---CKLDSFVANFIKVLCGQEIYNYALMEL 477

  Fly   672 HIDMDKMPLGKLSAHQIQSAYRV----VKEIYNVLECGSNT-AKLIDATNRFYTLIPHNFGVQLP 731
            .:|...:|:|.|:...::....|    |:::....|.|... |...|.::|:::|: |:
plant   478 GLDPPDLPMGMLTDIHLKRCEEVLLEFVEKVKTTKETGQKAEAMWADFSSRWFSLM-HS------ 535

  Fly   732 TLIETHQQIEDLRQMLDSLA-------EIEVAYSII---KSEDVSDACNPLDNHYAQIKTQLVAL 786
               ....::.|:.::.|..|       :|..|..:|   :.:.:.|   ||.:.|.::..::..:
plant   536 ---TRPMRLHDVNELADHAASAFETVRDINTASRLIGDMRGDTLDD---PLSDRYKKLGCKISVV 594

  Fly   787 DKNSEEFSILSQYVKNTHASTHKS---YDLKIVDVFKVSRQGEARRFKPFKKLHNRKLLWHGSRL 848
            ||.||::.::.:|::.|:.....|   |.:.:.:||.|.... .......|||.|:.|||.|||.
plant   595 DKESEDYKMVVKYLETTYEPVKVSDVEYGVSVQNVFAVESDA-IPSLDDIKKLPNKVLLWCGSRS 658

  Fly   849 TNFVGILSHGLRIAPPEAPPTGYMFGKGIYFADMVSKSANYCCTSQQNSTGLMLLSEVALG-DMM 912
            :|.:..:..|...|....|..|||||:.|..:|..:::|.|..|:.....|.::|:..:|| ::.
plant   659 SNLLRHIYKGFLPAVCSLPVPGYMFGRAIVCSDAAAEAARYGFTAVDRPEGFLVLAVASLGEEVT 723

  Fly   913 ECTSAKYINK-LSNNKHSCFGRGRTMPDPTKSYIRSDGVEIPYGETITDEHLKSSLLYNEYIVYD 976
            |.||.....| |.:.|....|.||...:.::.::..|.:::|.|..:..||..|.|.||||.|||
plant   724 EFTSPPEDTKTLEDKKIGVKGLGRKKTEESEHFMWRDDIKVPCGRLVPSEHKDSPLEYNEYAVYD 788

  Fly   977 VAQVNIQYLFRMEFKY 992
            ..|.:|::|  :|.||
plant   789 PKQTSIRFL--VEVKY 802

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Parp	NP_001104452.1	PLN03123	6..992	CDD:215590	210/859 (24%)
		zf-PARP	10..83	CDD:279039
		zf-PARP	114..193	CDD:279039	2/8 (25%)
		PADR1	270..322	CDD:285325	17/51 (33%)
		BRCT	382..454	CDD:214602	19/76 (25%)
		WGR_PARP1_like	526..629	CDD:153428	23/106 (22%)
		parp_like	645..988	CDD:238717	98/362 (27%)
AT5G22470	NP_001318618.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D909382at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10459
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920