Protein Alignment Parp1 and Parp1

DIOPT Version :10

• Sequence 1: NP_001104452.1
• Gene: Parp1 / 3355109
• FlyBaseID: FBgn0010247
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_061501736.1
• Gene: Parp1 / 1273904
• VectorBaseID: AGAMI1_007538
• Length: 1000
• Species: Anopheles gambiae
• Alignment Length: 1008
• Identity: 504/1008 - (50%)
• Similarity: 700/1008 - (69%)
• Gaps: 22/1008 - (2%)

  Fly     1 MDIE-LPYLAEYARTGRATCKGCKSTISKDTLRIAVMVQSAFHDAKVPNWFHKTCFFKNQRPSSV 64
            ||.| ||:||||:::.||.|:.||..|:||.||:|.||||..||.||..|:|..||||.|||::.
Mosquito     1 MDAEQLPFLAEYSKSNRAMCRLCKQAIAKDVLRLAAMVQSPMHDGKVAQWYHDDCFFKKQRPATE 65

  Fly    65 GDIQNIGNLRFADQKELTDLV----ENIQEVISAQLGKKRSKAFNLALKDFGIEYAKSSRSTCRG 125
            ||:.||..||:.|||::.|.:    :.:..|.....||||:.....:|||:|:|||.|.|:.|||
Mosquito    66 GDVANIEALRYEDQKKIRDAIAVFAKGVVPVAGKGKGKKRTAVEAQSLKDYGVEYAPSGRAMCRG 130

  Fly   126 CEQKINKDLVRLRKTVYDTEVGMKYGGQPLWHHLECFAQLRSELGWFASGEDMPGFQSLADDDQA 190
            ||.||.||.:|::|..|||||||||||||||||.||||:||||||:|...|.:||::|:..:||.
Mosquito   131 CEIKILKDEMRIKKVAYDTEVGMKYGGQPLWHHAECFAKLRSELGYFEKAESLPGYRSMKPEDQK 195

  Fly   191 KVKNAIPPIKSEELPDTKRAKMELSDTNE---EGEKKQRLKDQNDAYFRFRDDIKN-KMKKKDID 251
            .:|..:|.||:|::| .|:.|.|:.|..:   :..:::::.:|..||:..||.:|: .:||.::.
Mosquito   196 ILKGLLPAIKAEDVP-AKKVKEEVKDEVDKAADATEEKKMAEQQKAYYAIRDKLKSLGVKKSELI 259

  Fly   252 ILLKFNNQQPVTGDTEKLFDQTADLLTFGAIESCSECNSCQFIVNKSGYICNGNHSEWTKCNKLL 316
            .:|..|.|....|: :.:.|:..|.|.|||:|.||:|.. |:...||.|:|.|:.|.|.||....
Mosquito   260 EILSLNKQDIPEGN-DPVLDRVCDTLMFGALERCSKCGG-QYAFQKSAYVCQGDLSAWVKCMNTE 322

  Fly   317 KEPTRSACIVPKELKALYNFLNTVKEIPSTRIFNNFPPNKSTFSRSLLKTNKNNDVLVRPTIPRI 381
            |.|.|....:|:|||::|:||...|.:.|.|:....||:.:|..:.:   .|..::...|.|.|.
Mosquito   323 KAPPRKKTKIPEELKSVYSFLKRYKSVISDRVVRYVPPSVNTVMKGV---KKEEELPSEPKIKRE 384

  Fly   382 SPPLYNLKFSIIGLKNQHK-ELRKRIENLGGKFEVKISENTIAIISTELEIQKKSTRMKFAEELG 445
            .||||:::|.|:|.....| :|:.:|:.||||...||:.:|.|||||..|:::..:||..|:||.
Mosquito   385 KPPLYDMEFVILGKTATPKDQLKLKIQKLGGKVVTKIASHTAAIISTPEEVERLGSRMAEAKELQ 449

  Fly   446 IHIVPIEFLDFVEADTEGAIKYINSTCICSWGTDPKSRIP-KETTKSLNSNSIYTKSMPVSRTFK 509
            |.:||.:||:.|...  |||.:|.|..||.||:||..||| :|.:||....|||.||:|.....:
Mosquito   450 IQVVPEDFLEDVVGG--GAISFITSRSICDWGSDPLKRIPTEEESKSRTKKSIYEKSVPAKMKLQ 512

  Fly   510 VKDGLAVDPDSGLEDIAHVYVDSNNKYSVVLGLTDIQRNKNSYYKVQLLKADKKEKYWIFRSWGR 574
            ||.||.|||||||.|.||||...:..|:.||...|||::|||:||:|:|:.|.|:|||:||:|||
Mosquito   513 VKSGLVVDPDSGLADKAHVYKFHDVIYNCVLNKVDIQKDKNSFYKMQVLEGDTKKKYWLFRAWGR 577

  Fly   575 IGTNIGNSKLEEFDTSESAKRNFKEIYADKTGNEYEQRDN-FVKRTGRMYPIEIQYDDDQKLVKH 638
            |||.||.:|:|.|.:::||...|::::.:||||::.:.|: :.|..|..|||||.|.:.:.....
Mosquito   578 IGTTIGGNKVENFSSADSAMSAFEDLFQEKTGNDWVRHDSVYSKMPGAFYPIEIDYSETKTKRLA 642

  Fly   639 ESHFFTSKLEISVQNLIKLIFDIDSMNKTLMEFHIDMDKMPLGKLSAHQIQSAYRVVKEIYNVLE 703
            |:....|||..:||:|::::||:|:||:.:|||.:||:||||||||..|:|||.:|:.||..::.
Mosquito   643 ENSGIKSKLAPAVQDLVRMLFDVDAMNRVMMEFELDMEKMPLGKLSKRQLQSAMKVLSEISTLIG 707

  Fly   704 CGSNTAKLIDATNRFYTLIPHNFGVQLPTLIETHQQIEDLRQMLDSLAEIEVAYSIIKSEDVS-- 766
            .|.:.|:.|.|:||||:.|||||||....:::|.:|:::.:.||:||.|||.|||::...|.|
Mosquito   708 SGGSNAEFIAASNRFYSYIPHNFGVSSVKVLDTIEQVKEKQTMLESLMEIEFAYSLLNDGDESAQ 772

  Fly   767 DACNPLDNHYAQIKTQLVALDKNSEEFSILSQYVKNTHASTHKSYDLKIVDVFKVSRQGEARRFK 831
            |..||||.||.|:||.:..:.::||||::|.|||:||||.||::|:|::.::|::.|:||.||::
Mosquito   773 DGKNPLDAHYDQLKTSIEPMARDSEEFALLEQYVRNTHAETHRTYELEVAEIFRIKRKGEDRRYQ 837

  Fly   832 PFKKLHNRKLLWHGSRLTNFVGILSHGLRIAPPEAPPTGYMFGKGIYFADMVSKSANYCCTSQQN 896
            ||||||||||||||||||||.|||::||:|||||||.||||||||||||||||||||||||:..:
Mosquito   838 PFKKLHNRKLLWHGSRLTNFAGILTNGLKIAPPEAPVTGYMFGKGIYFADMVSKSANYCCTNVAD 902

  Fly   897 STGLMLLSEVALGDMMECTSAKYINKLSNNKHSCFGRGRTMPDPTKSYIRSDGVEIPYGETITDE 961
            ||||:||.|||||||.|.|.|.|:.|||..|||..|.|||.||||.|::|.||||||.|:.:::|
Mosquito   903 STGLLLLCEVALGDMQEYTQAHYVTKLSTGKHSVKGIGRTQPDPTGSHVRPDGVEIPMGKGVSNE 967

  Fly   962 HLKSSLLYNEYIVYDVAQVNIQYLFRMEFKYSY 994
            .|||||||||:|||||.|||.||||:|.|||.|
Mosquito   968 KLKSSLLYNEFIVYDVGQVNCQYLFKMNFKYKY 1000

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Parp1	NP_001104452.1	PLN03123	6..992	CDD:215590	497/998 (50%)
Parp1	XP_061501736.1	None