Protein Alignment Parp1 and parp1

DIOPT Version :10

• Sequence 1: NP_001104452.1
• Gene: Parp1 / 3355109
• FlyBaseID: FBgn0010247
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_031757916.1
• Gene: parp1 / 100490557
• XenbaseID: XB-GENE-974935
• Length: 1013
• Species: Xenopus tropicalis
• Alignment Length: 1029
• Identity: 436/1029 - (42%)
• Similarity: 605/1029 - (58%)
• Gaps: 75/1029 - (7%)

  Fly     7 YLAEYARTGRATCKGCKSTISKDTLRIAVMVQSAFHDAKVPNWFHKTCFFKNQRPSSVGDIQNIG 71
            |.||||::|||:||.|...|:|::||:|:||||...|.|||:|.|.:||:|..|..|.|||....
 Frog     9 YRAEYAKSGRASCKKCGDNIAKESLRLALMVQSPMFDGKVPHWHHYSCFWKRARVLSHGDIDGFT 73

  Fly    72 NLRFADQKELTDLVENIQEVISAQLGKKRSKAFNLALKDFGIEYAKSSRSTCRGCEQKINKDLVR 136
            .||:.||:::...:|.......|....|..|. .:.|.||.:|||||:||||:|||:||.|..:|
 Frog    74 ELRWDDQEKIKKAIETGGASAGAGGDAKGGKG-EMTLNDFAVEYAKSNRSTCKGCEKKIEKGQIR 137

  Fly   137 LRKTVYDTE---VGMKYGGQPLWHHLECFAQLRSELGWFA--SGEDMPGFQSLADDDQAKVKNAI 196
            :.|.:.|.|   :||    ...|:|.:||...|.|||:..  |...:..|..|..:|:..:|..:
 Frog   138 ISKKMVDVERPQLGM----IDRWYHSDCFVSCREELGFLPSYSASQLKAFSILKAEDKDALKAML 198

  Fly   197 PPIKSEELPDTKRAKMELSDTNEEGEKK-------------QRLKDQNDAYFRFRDDIKNKMKKK 248
            |.:|:|     .:.|.:..|.:..|.||             :.||:|.:..:..:|::|......
 Frog   199 PAVKNE-----GKRKADEVDASSAGTKKKLKKEKEKESKLEKLLKEQTELIWHIKDELKKVCSTN 258

  Fly   249 DIDILLKFNNQQPVTGDTEKLFDQTADLLTFGAIESCSECNSCQFIVNKSGYICNGNHSEWTKCN 313
            |:..||..|.||..:|:| .:.|:.:|.:.|||:..|.|| |.||:.....|.|.|:.|.||||.
 Frog   259 DLKELLIANKQQVPSGET-NILDRVSDGMAFGALLPCEEC-SGQFVFKSDAYYCTGDLSAWTKCV 321

  Fly   314 KLLKEPTRSACIVPKELKALYNFLNTVKEIPSTRIF------NNFPPNKSTFSRSLLKTNKNNDV 372
            ...:.|.|...:.|||.          .|:|..:.|      ..|||..:....|.....|....
 Frog   322 AKTQTPNRKDWVTPKEF----------HEVPYLKKFKFKRQDRAFPPCAAPTPISPPAAPKPAPT 376

  Fly   373 LVRPTIPRISPPLYNLKFSIIGLKNQHK-ELRKRIENLGGKFEVKISENTIAIISTELEIQKKST 436
             |..|:|. ..||.|.|..:||..:::| |::..||.||||......:.|:. |||:.|::|.|.
 Frog   377 -VEETVPE-GKPLTNAKVLVIGKLSKNKDEVKALIEGLGGKVTGSAHKATLC-ISTKKEVEKMSK 438

  Fly   437 RMKFAEELGIHIVPIEFLDFVEADTEGAIKYINSTCICSWGTDPKSRIPKETTKSLNSNSIYTKS 501
            :|:..:...:.:|..:||..||:. :...:.::...|.|||.:.|....:.|.|..:|.....||
 Frog   439 KMEDVKAANVRVVSDDFLKEVESG-KSVQELLSQYGISSWGAEVKQEAVQPTEKQPSSAPAAGKS 502

  Fly   502 MPVSRTFK------------VKDGLAVDPDSGLEDIAHVYVDSNNKYSVVLGLTDIQRNKNSYYK 554
            ....:..|            ||.|.|:||||||||..||.......:|..|||.||.|..|||||
 Frog   503 SGKVKEEKGSNKSEKKMKLTVKGGAAIDPDSGLEDSCHVLEKGGKIFSATLGLVDITRGTNSYYK 567

  Fly   555 VQLLKADKKEKYWIFRSWGRIGTNIGNSKLEEFDTSESAKRNFKEIYADKTGNEYEQRDNFVKRT 619
            :||::.|:..:||:||||||:||.||::||||..:.|.|..:|..:|.:||||.:.. .||.|..
 Frog   568 LQLIEHDRNSRYWVFRSWGRVGTVIGSNKLEEMSSKEDAIDHFLNLYQEKTGNAWHS-PNFTKYP 631

  Fly   620 GRMYPIEIQYDDDQKLVKHES--HFFTSKLEISVQNLIKLIFDIDSMNKTLMEFHIDMDKMPLGK 682
            .:.||:||.|..::.:||..|  ....|||...||.|||||||::||.|.::||.||:.||||||
 Frog   632 NKFYPLEIDYGQEEDVVKKLSVGAGTKSKLAQPVQELIKLIFDVESMKKAMVEFEIDLQKMPLGK 696

  Fly   683 LSAHQIQSAYRVVKEIYNVLECGSNTAKLIDATNRFYTLIPHNFGVQLPTLIETHQQIEDLRQML 747
            ||..||||||.::.::...:...|:.|:|:|.:|:|||||||:||::.|.|:...:.|:...|||
 Frog   697 LSKRQIQSAYSILNQVQQAVSESSSEARLLDLSNQFYTLIPHDFGMKKPPLLNNLEYIQAKVQML 761

  Fly   748 DSLAEIEVAYSIIKSEDVSDACNPLDNHYAQIKTQLVALDKNSEEFSILSQYVKNTHASTHKSYD 812
            |:|.:||||||:::........:|:|..|.:|||.:..:||.|||..|:..|||||||.||.:||
 Frog   762 DNLLDIEVAYSLLRGGADDGEKDPIDVKYEKIKTDIKVVDKESEESRIIRDYVKNTHAETHNAYD 826

  Fly   813 LKIVDVFKVSRQGEARRFKPFKKLHNRKLLWHGSRLTNFVGILSHGLRIAPPEAPPTGYMFGKGI 877
            |:::::||:.|:||.:|:||||:||||:|||||||.|||.||||.||||||||||.|||||||||
 Frog   827 LEVLEIFKIEREGEYQRYKPFKQLHNRQLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGI 891

  Fly   878 YFADMVSKSANYCCTSQQNSTGLMLLSEVALGDMMECTSAKYINKLSNNKHSCFGRGRTMPDPTK 942
            |||||||||||||.....|..||:||.|||||:|.|..:|.:|.||...|||..|.|||.|||:.
 Frog   892 YFADMVSKSANYCNAMPGNPIGLILLGEVALGNMHELRAASHITKLPKGKHSVKGLGRTAPDPSA 956

  Fly   943 SYIRSDGVEIPYGE----TITDEHLKSSLLYNEYIVYDVAQVNIQYLFRMEFKY 992
            : ::.|||::|.|:    .|||    :||||||||||||||||::||.:::|.|
 Frog   957 T-VKLDGVDVPLGKGSATNITD----ASLLYNEYIVYDVAQVNLKYLLKLKFNY 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Parp1	NP_001104452.1	PLN03123	6..992	CDD:215590	435/1027 (42%)
parp1	XP_031757916.1	PLN03123	4..1006	CDD:215590	436/1029 (42%)