Protein Alignment Parp and parp2

DIOPT Version :9

• Sequence 1: NP_001104452.1
• Gene: Parp / 3355109
• FlyBaseID: FBgn0010247
• Length: 994
• Species: Drosophila melanogaster
• Sequence 2: XP_021334004.1
• Gene: parp2 / 100007906
• ZFINID: ZDB-GENE-031113-6
• Length: 649
• Species: Danio rerio
• Alignment Length: 599
• Identity: 229/599 - (38%)
• Similarity: 350/599 - (58%)
• Gaps: 42/599 - (7%)

  Fly   415 VKISE-NTIAIISTELEIQK-KSTRMKFAEEL-------GIHIVPIEFLDFVEADTEGAIKYINS 470
            ||::: ||::....::.:|| ||..:.....|       |:    ::..:..|.:.|..:
Zfish    70 VKMTQTNTVSKYKRKIRLQKVKSEDLNEGNALNGNKKATGV----VQIKEEKEEEEEQPV----- 125

  Fly   471 TCICSWGTDPKSRIPKETTKSLNSNSIYTKSMPVSRTFKVKDGLAVDPDSGLE-DIAHVYVDSNN 534
                    ..|.|....:.|:.....:..:...|.:|..:|....|||:...: ..||||.:..:
Zfish   126 --------SKKRRNEGRSQKANKDKPVVKEECEVVKTLVMKGKAPVDPECKAKLGKAHVYNEGAD 182

  Fly   535 KYSVVLGLTDIQRNKNSYYKVQLLKADKKEKYWIFRSWGRIGTNIGNSKLEEFDTS-ESAKRNFK 598
            .|.|:|..|::|.|.|.||.:|||:.|..:.|.::..|||:| .:|.:.|.....: ..||..||
Zfish   183 VYDVMLNQTNLQFNNNKYYLIQLLEDDSAKAYSVWLRWGRVG-KVGQNNLVSCGANLAQAKDTFK 246

  Fly   599 EIYADKTGNEYEQRDNFVKRTGRMYPIEIQYDDDQK-----LVKHESHFFTSKLEISVQNLIKLI 658
            :.:.|||.||:|.|.:|.|..|:...:.:.|..:.|     :|...:.....:|...||:|::||
Zfish   247 KKFFDKTKNEWEHRASFEKVAGKYDMVFMDYSTEDKGEEKAVVPSATQKKPCQLNSKVQSLLELI 311

  Fly   659 FDIDSMNKTLMEFHIDMDKMPLGKLSAHQIQSAYRVVKEIYNVLECGSNTAKLIDATNRFYTLIP 723
            .|:.:|.:.::|...|..|.|||||:|.||::.|..:|.|...|:...:..:|:||.|:|||.||
Zfish   312 CDLKAMEECVLEMKFDTKKAPLGKLTAEQIRAGYASLKRIEECLKKKGSNKELLDACNQFYTRIP 376

  Fly   724 HNFGVQLPTLIETHQQIEDLRQMLDSLAEIEVAYSIIKSEDVSDACNPLDNHYAQIKTQLVALDK 788
            |:||::.|.:|.:.:::::...:|::|::|::|..:::|...||. :|||..|..:..||..||.
Zfish   377 HDFGLRTPPIIRSEEELKEKITLLETLSDIQIAVKMVQSNVKSDE-HPLDRQYHSLNCQLQPLDT 440

  Fly   789 NSEEFSILSQYVKNTHASTHKSYDLKIVDVFKVSRQGEARRFKPFKKLHNRKLLWHGSRLTNFVG 853
            :|.|:.::.:|:|:|||.||..|.:.::|||.|.|:.|...|.  .:|.||.||||||||:|:||
Zfish   441 DSNEYKVIEKYLKSTHAPTHTDYTMTLLDVFAVEREVEKDNFN--SELQNRMLLWHGSRLSNWVG 503

  Fly   854 ILSHGLRIAPPEAPPTGYMFGKGIYFADMVSKSANYCCTSQQNSTGLMLLSEVALGDMMECTSAK 918
            |||.|||:||.|||.||||||||||||||.|||||||..||:|:.||:|||||||||..|...|.
Zfish   504 ILSQGLRVAPAEAPVTGYMFGKGIYFADMSSKSANYCFASQKNNQGLLLLSEVALGDSNELLDAD 568

  Fly   919 Y-INKLSNNKHSCFGRGRTMPDPTKSYIRSDGVEIPYGETI-TDEHLKS--SLLYNEYIVYDVAQ 979
            | .::|.:.|||..|.|:|.|||.|| :..:||.:|.|.:: |....|.  ||||||||||:.||
Zfish   569 YNADQLPSGKHSTKGLGQTAPDPKKS-VSLNGVTVPLGPSVKTGVGQKGGYSLLYNEYIVYNPAQ 632

  Fly   980 VNIQYLFRMEFKYS 993
            :.::||.|::|.:|
Zfish   633 IQMKYLLRVQFNFS 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Parp	NP_001104452.1	PLN03123	6..992	CDD:215590	228/596 (38%)
		zf-PARP	10..83	CDD:279039
		zf-PARP	114..193	CDD:279039
		PADR1	270..322	CDD:285325
		BRCT	382..454	CDD:214602	10/47 (21%)
		WGR_PARP1_like	526..629	CDD:153428	38/103 (37%)
		parp_like	645..988	CDD:238717	164/346 (47%)
parp2	XP_021334004.1	WWE	23..86	CDD:308464	4/15 (27%)
		PARP_reg	98..645	CDD:332154	220/568 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1037
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D121455at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101236
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.720