DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tim17b and TIMM17B

DIOPT Version :9

Sequence 1:	NP_001015401.1	Gene:	Tim17b / 3355107	FlyBaseID:	FBgn0263977	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_001161419.1	Gene:	TIMM17B / 10245	HGNCID:	17310	Length:	222	Species:	Homo sapiens

Alignment Length:	215	Identity:	112/215 - (52%)
Similarity:	127/215 - (59%)	Gaps:	54/215 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEEYAREPCPYRIVDDCGGAFAMGCIGGGVFQAIKGFRNAP------------------------ 41
            ||||||||||:||||||||||.||.||||||||||||||||
Human     1 MEEYAREPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVCRLLSEAPLFIYSCSRSVSPTVN 65

  Fly    42 --------------------------SGLNRRLVGSIIAIKTRSPVIAGNFAVWGGMFSTIDCTL 80
                                      .|:..||.||..|::.|:|.|.|:||||||:||||||.|
Human    66 VSSERAESRPTLFMAVSLHMAWCLAHIGIRHRLRGSANAVRIRAPQIGGSFAVWGGLFSTIDCGL 130

  Fly    81 VHFRKKEDPWNSIISGAATGGILAARNGVPAMAGSAIIGGVLLALIEGVGILFTRISADQFKNPI 145
            |..|.||||||||.|||.||.:||||:|..||.|||::||:|||||||||||.||.:|.||:|..
Human   131 VRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQQFRNAP 195

  Fly   146 PPAEDPVAL----GDPGRNF 161
            |..|||..|    |.|...:
Human   196 PFLEDPSQLPPKDGTPAPGY 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tim17b	NP_001015401.1	Tim17	1..155	CDD:295283	110/207 (53%)
TIMM17B	NP_001161419.1	Tim17	1..221	CDD:295283	112/215 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152393
Domainoid	1	1.000	168	1.000	Domainoid score	I3821
eggNOG	1	0.900	-	-		E1_COG5596
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4620
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3506
Isobase	1	0.950	-	0	Normalized mean entropy	S575
OMA	1	1.010	-	-		QHG54844
OrthoDB	1	1.010	-	-		D1590221at2759
OrthoFinder	1	1.000	-	-		FOG0001103
OrthoInspector	1	1.000	-	-		mtm8479
orthoMCL	1	0.900	-	-		OOG6_101935
Panther	1	1.100	-	-	LDO	PTHR10485
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2313
SonicParanoid	1	1.000	-	-		X753
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750