DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg-2 and Capns2

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001102850.1	Gene:	Capns2 / 679870	RGDID:	1583620	Length:	247	Species:	Rattus norvegicus

Alignment Length:	158	Identity:	43/158 - (27%)
Similarity:	86/158 - (54%)	Gaps:	13/158 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 DVFQRVDKDRSGHISADELQVALSNGTWSAFNPETIRLMIGMFDRENKGTVSFKDFGALWKYVTD 80
            |:...::|..|.|   .||:.       ..|:.:|.|.::.:.|.:..|.:.|::|..||..:..
  Rat    98 DLMNILNKVLSKH---KELKT-------DGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIKK 152

  Fly    81 WQNCFRSFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKF-DRFGRGTILFDDFIQCCIVL 144
            ||..|:.:|.|:||.:..::|..|:.:.|::|::.|..:::|:: |.  .|::.|::||.|.:.|
  Rat   153 WQCVFKQYDSDHSGFLRSSQLHGAMQAAGFQLNEQLYLMIVRRYADE--DGSMDFNNFISCLVRL 215

  Fly   145 YTLTTAFRQHDTDLDGIITIHYEQFLSM 172
            ..:..||:..|.|.||:|.:...::|.:
  Rat   216 DAMFRAFKTLDRDRDGLIRVSIREWLQL 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	12/54 (22%)
		EFh	16..71	CDD:238008	12/54 (22%)
		EF-hand_7	82..139	CDD:290234	16/57 (28%)
		EFh	85..139	CDD:238008	15/54 (28%)
Capns2	NP_001102850.1	EFh	123..168	CDD:298682	14/44 (32%)
		EF-hand_7	154..209	CDD:290234	15/56 (27%)
		EFh	154..209	CDD:298682	15/56 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010