DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg-2 and capns2

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001016161.1	Gene:	capns2 / 548915	XenbaseID:	XB-GENE-5764367	Length:	234	Species:	Xenopus tropicalis

Alignment Length:	165	Identity:	47/165 - (28%)
Similarity:	89/165 - (53%)	Gaps:	11/165 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 FQRVDKDRSG---HISADELQVALS-------NGTWSAFNPETIRLMIGMFDRENKGTVSFKDFG 72
            |:|:....:|   .:||.||...|:       :.....|:.::.|.|:.:.|.::.|.:.|::|.
Frog    67 FRRLFSQLAGDDMEVSATELMGILNKVIAKHQDLKTDGFSADSCRSMVAVMDSDSTGKLGFEEFK 131

  Fly    73 ALWKYVTDWQNCFRSFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKFDRFGRGTILFDDF 137
            .||..:..||..::.:|.|.||.|.:.||..|.|:.|::|:..|.|:::|::.. .:|.:.||::
Frog   132 YLWDNIKKWQGVYKRYDTDRSGTIGRNELPGAFTAAGFQLNGQLYDMIIRRYSD-EKGDMDFDNY 195

  Fly   138 IQCCIVLYTLTTAFRQHDTDLDGIITIHYEQFLSM 172
            |.|.:.|..:..||:..|.|.||.|.:..:::|.:
Frog   196 ICCLVRLDAMFRAFKTLDKDGDGQIKVTIQEWLQL 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	14/62 (23%)
		EFh	16..71	CDD:238008	14/62 (23%)
		EF-hand_7	82..139	CDD:290234	18/56 (32%)
		EFh	85..139	CDD:238008	17/53 (32%)
capns2	NP_001016161.1	EFh_PEF_CPNS1_2	66..234	CDD:320063	47/165 (28%)
		EF-hand motif	66..94	CDD:320063	8/26 (31%)
		EF-hand motif	108..138	CDD:320063	8/29 (28%)
		EF-hand motif	139..169	CDD:320063	11/29 (38%)
		EF-hand motif	175..203	CDD:320063	8/28 (29%)
		EF-hand motif	204..234	CDD:320063	8/27 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920