DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Alg-2 and capn2a

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001013519.1	Gene:	capn2a / 541374	ZFINID:	ZDB-GENE-050320-69	Length:	698	Species:	Danio rerio

Alignment Length:	152	Identity:	43/152 - (28%)
Similarity:	73/152 - (48%)	Gaps:	12/152 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ISADELQVAL-------SNGTWSAFNPETIRLMIGMFDRENKGTVSFKDFGALWKYVTDWQNCFR 86
            |||.||:...       ::.....|:.:|.|:|:.:.|....|.:...:|..|||.:..:...::
Zfish   546 ISASELRTIFNKIVAKRTDIKTDGFSLDTCRVMVNLMDESGNGKLGLTEFATLWKKIQKYLGIYK 610

  Fly    87 SFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKFDRFGRG--TILFDDFIQCCIVLYTLTT 149
            ..|.|.||.:...|::.||...|:.|:|.:...|..   |:|..  ||.||:|:.|.:.|..:..
Zfish   611 KNDMDGSGCMSTPEMRMALKEAGFSLNDCIHQSLAA---RYGDADMTIDFDNFVSCVMRLEMMFK 672

  Fly   150 AFRQHDTDLDGIITIHYEQFLS 171
            .|::.|.|..|.|.:.:.|:||
Zfish   673 VFKRMDIDHSGFIELDFFQWLS 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	11/48 (23%)
		EFh	16..71	CDD:238008	11/48 (23%)
		EF-hand_7	82..139	CDD:290234	18/58 (31%)
		EFh	85..139	CDD:238008	18/55 (33%)
capn2a	NP_001013519.1	Peptidase_C2	46..339	CDD:279042
		Calpain_III	354..505	CDD:279416
		EF-hand_8	542..601	CDD:290545	14/54 (26%)
		EFh	575..630	CDD:298682	14/54 (26%)
		FRQ1	602..>694	CDD:227455	26/94 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910