DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Alg-2 and gca

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001005585.1	Gene:	gca / 449543	ZFINID:	ZDB-GENE-040930-3	Length:	205	Species:	Danio rerio

Alignment Length:	172	Identity:	56/172 - (32%)
Similarity:	99/172 - (57%)	Gaps:	7/172 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PDQQFLWDVFQRVDKDRSGHISADELQVALS----NGTWSAFNPETIRLMIGMFDRENKGTVSFK 69
            |.|..:|..|..: ..:.|.:.|:|||..|:    :|:::.|:.||.|:||.:.||:..|.:.|.
Zfish    37 PAQDPMWGYFTAI-AGQDGEVDAEELQRCLTQTGISGSYTPFSLETCRIMIALLDRDYTGKMGFN 100

  Fly    70 DFGALWKYVTDWQNCFRSFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKFDRFGRGTILF 134
            :|..|:..:..|:..|...|||:||.::..|:..::.:.|||:|..::|.:::::.|.|:  |.|
Zfish   101 EFKELFGVLNGWKQNFMMVDRDHSGTVEPYEMSQSIANMGYRVSPRVLDAIVKRYSRSGK--IYF 163

  Fly   135 DDFIQCCIVLYTLTTAFRQHDTDLDGIITIHYEQFLSMVFSL 176
            ||::.||:.|..||..||:.||...|::...|:.|:....||
Zfish   164 DDYVACCVKLKALTDHFRRRDTMQQGMVNFQYDDFILCTISL 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	18/58 (31%)
		EFh	16..71	CDD:238008	18/58 (31%)
		EF-hand_7	82..139	CDD:290234	18/56 (32%)
		EFh	85..139	CDD:238008	18/53 (34%)
gca	NP_001005585.1	EFh	52..106	CDD:298682	18/53 (34%)
		EFh	82..132	CDD:298682	16/49 (33%)
		EFh	116..168	CDD:298682	18/53 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54126
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	1	1.000	-	-		FOG0000697
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100410
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830