DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg-2 and capn2l

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_001003485.1	Gene:	capn2l / 445091	ZFINID:	ZDB-GENE-050417-341	Length:	700	Species:	Danio rerio

Alignment Length:	151	Identity:	42/151 - (27%)
Similarity:	78/151 - (51%)	Gaps:	8/151 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ISADELQVALSNG-------TWSAFNPETIRLMIGMFDRENKGTVSFKDFGALWKYVTDWQNCFR 86
            |||.|||..|:|.       ....|:.||.|.|:.:.|::..|.:...:|..||..:..:.:.:.
Zfish   548 ISAFELQKILNNVIAKRKEIKTDGFSLETCRNMVNLLDKDGTGKLGLLEFKILWTKIELFVDVYS 612

  Fly    87 SFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKFDRFGRGTILFDDFIQCCIVLYTLTTAF 151
            ..|:|.||.:...|::.|:...|:.|::.|..:|:.::.. ...||.||:|:.|.|.|..:..||
Zfish   613 KNDKDQSGTMSSMEMREAVEKAGFSLNNALHQILVARYSE-SNLTIDFDNFVACLIRLECMFKAF 676

  Fly   152 RQHDTDLDGIITIHYEQFLSM 172
            :..|.|.:|.:.::..::|::
Zfish   677 KVLDKDKNGTVELNMIEWLNV 697

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	15/48 (31%)
		EFh	16..71	CDD:238008	15/48 (31%)
		EF-hand_7	82..139	CDD:290234	15/56 (27%)
		EFh	85..139	CDD:238008	15/53 (28%)
capn2l	NP_001003485.1	Peptidase_C2	46..342	CDD:279042
		Calpain_III	356..507	CDD:279416
		EFh	577..631	CDD:298682	12/53 (23%)
		FRQ1	604..>695	CDD:227455	23/91 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910