DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg-2 and Gca

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_663498.1	Gene:	Gca / 227960	MGIID:	1918521	Length:	220	Species:	Mus musculus

Alignment Length:	174	Identity:	62/174 - (35%)
Similarity:	95/174 - (54%)	Gaps:	7/174 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAYNHDGMPDQQFLWDVFQRVDKDRSGHISADELQVALS----NGTWSAFNPETIRLMIGMFDRE 61
            :.|:....|....:|..|..| ..:.|.:.|:|||..|:    :||::.|:.||.|:||.|.||:
Mouse    44 LGYSDSYSPADDSMWTYFTAV-AGQDGEVDAEELQRCLTQSGISGTYAPFSLETCRIMIAMLDRD 107

  Fly    62 NKGTVSFKDFGALWKYVTDWQNCFRSFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKFDR 126
            ..|.:.|.:|..||..:..|:..|.:.|:|.||.::..||..|:...|||||...:..::|::.:
Mouse   108 YTGKMGFNEFKELWAALNAWKQNFMTIDQDQSGTVEHHELSQAIALMGYRLSPQTLAAIVRRYSK 172

  Fly   127 FGRGTILFDDFIQCCIVLYTLTTAFRQHDTDLDGIITIHYEQFL 170
            .||  |.|||::.||:.|..||..||:.|....||:...||.||
Mouse   173 NGR--IFFDDYVACCVKLRALTDFFRRRDHLQQGIVNFMYEDFL 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	21/58 (36%)
		EFh	16..71	CDD:238008	21/58 (36%)
		EF-hand_7	82..139	CDD:290234	20/56 (36%)
		EFh	85..139	CDD:238008	20/53 (38%)
Gca	NP_663498.1	EFh	67..122	CDD:238008	21/54 (39%)
		EF-hand_7	67..120	CDD:290234	20/52 (38%)
		EFh	97..152	CDD:298682	20/54 (37%)
		EF-hand_7	128..183	CDD:290234	20/56 (36%)
		EFh	131..183	CDD:298682	20/53 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54126
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000697
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100410
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820