Protein Alignment Alg-2 and Pdcd6

DIOPT Version :9

• Sequence 1: NP_001104459.2
• Gene: Alg-2 / 3355106
• FlyBaseID: FBgn0086378
• Length: 178
• Species: Drosophila melanogaster
• Sequence 2: NP_035181.1
• Gene: Pdcd6 / 18570
• MGIID: 109283
• Length: 191
• Species: Mus musculus
• Alignment Length: 169
• Identity: 116/169 - (68%)
• Similarity: 136/169 - (80%)
• Gaps: 0/169 - (0%)

  Fly     8 MPDQQFLWDVFQRVDKDRSGHISADELQVALSNGTWSAFNPETIRLMIGMFDRENKGTVSFKDFG 72
            :|||.|||:|||||||||||.||.:|||.|||||||:.|||.|:|.:|.|||||||..|:|.:|.
Mouse    22 LPDQSFLWNVFQRVDKDRSGVISDNELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFT 86

  Fly    73 ALWKYVTDWQNCFRSFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKFDRFGRGTILFDDF 137
            .:|||:|||||.||::||||||.|||.|||.||:.|||||||...|:|:|||||.|||.|.||||
Mouse    87 GVWKYITDWQNVFRTYDRDNSGMIDKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDF 151

  Fly   138 IQCCIVLYTLTTAFRQHDTDLDGIITIHYEQFLSMVFSL 176
            ||.||||..||..||::|||.||.|.:.|||:||||||:
Mouse   152 IQGCIVLQRLTDIFRRYDTDQDGWIQVSYEQYLSMVFSI 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	38/54 (70%)
		EFh	16..71	CDD:238008	38/54 (70%)
		EF-hand_7	82..139	CDD:290234	40/56 (71%)
		EFh	85..139	CDD:238008	38/53 (72%)
Pdcd6	NP_035181.1	EFh_PEF_ALG-2	27..191	CDD:320058	113/164 (69%)
		EF-hand motif	27..56	CDD:320058	23/28 (82%)
		EF-hand motif	64..93	CDD:320058	16/28 (57%)
		EF-hand motif	94..123	CDD:320058	20/28 (71%)
		EF-hand motif	130..159	CDD:320058	20/28 (71%)
		EF-hand motif	161..189	CDD:320058	17/27 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842828
Domainoid	1	1.000	93	1.000	Domainoid score	I7554
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7880
Inparanoid	1	1.050	245	1.000	Inparanoid score	I3270
Isobase	1	0.950	-	0	Normalized mean entropy	S1635
OMA	1	1.010	-	-		QHG54126
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	1	1.000	-	-		FOG0000697
OrthoInspector	1	1.000	-	-		oto95324
orthoMCL	1	0.900	-	-		OOG6_100410
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4200
SonicParanoid	1	1.000	-	-		X1327
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.790