DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Alg-2 and Capns1

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_033925.2	Gene:	Capns1 / 12336	MGIID:	88266	Length:	268	Species:	Mus musculus

Alignment Length:	152	Identity:	45/152 - (29%)
Similarity:	78/152 - (51%)	Gaps:	10/152 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 ISADELQVALSNGT-------WSAFNPETIRLMIGMFDRENKGTVSFKDFGALWKYVTDWQNCFR 86
            :||.||...|:...       ...|..:|.|.|:.:.|.:..|.:.|::|..||..:..||..::
Mouse   115 VSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIKKWQAIYK 179

  Fly    87 SFDRDNSGNIDKTELKTALTSFGYRLSDHLIDVLLRKF-DRFGRGTILFDDFIQCCIVLYTLTTA 150
            .||.|.||.|...||..|..:.|:.|::||..:::|:: |.  .|.:.||:||.|.:.|..:..|
Mouse   180 RFDTDRSGTIGSHELPGAFEAAGFHLNEHLYSMIIRRYADE--SGNMDFDNFISCLVRLDAMFRA 242

  Fly   151 FRQHDTDLDGIITIHYEQFLSM 172
            |:..|.:..|.|.::.:::|.:
Mouse   243 FKSLDKNGTGQIQVNIQEWLQL 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	12/48 (25%)
		EFh	16..71	CDD:238008	12/48 (25%)
		EF-hand_7	82..139	CDD:290234	20/57 (35%)
		EFh	85..139	CDD:238008	19/54 (35%)
Capns1	NP_033925.2	EFh_PEF_CPNS1_2	100..268	CDD:320063	45/152 (30%)
		EF-hand motif	100..128	CDD:320063	5/12 (42%)
		EF-hand motif	142..172	CDD:320063	9/29 (31%)
		EF-hand motif	173..203	CDD:320063	11/29 (38%)
		EF-hand motif	209..237	CDD:320063	9/29 (31%)
		EF-hand motif	238..268	CDD:320063	6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1330600at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920