DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg-2 and capn10l

DIOPT Version :9

Sequence 1:	NP_001104459.2	Gene:	Alg-2 / 3355106	FlyBaseID:	FBgn0086378	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	XP_031758129.1	Gene:	capn10l / 100497805	XenbaseID:	XB-GENE-5889689	Length:	708	Species:	Xenopus tropicalis

Alignment Length:	186	Identity:	43/186 - (23%)
Similarity:	76/186 - (40%)	Gaps:	39/186 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 YNHDGMPDQQFLWDVFQRVD---------------------------KDRSGHISADELQVALSN 40
            :|.|...:..||..||.|..                           ..:.|.:::.:||..|::
Frog   502 FNADRSQESSFLLQVFLRSQGCTVELGDSQSFLKNEEKTQEETFMKYATQGGKMNSQDLQKFLND 566

  Fly    41 GTWSAFNP--------ETIRLMIGMFDRENKGTVSFKDFGALWKYVTDWQNCFRSFDRDNSGNID 97
            .....|.|        |..|.|:...|....|.:..:.|..||:|:..::..|...|.|.:|.|.
Frog   567 VISKGFAPHGGIRFSTEASRSMLASMDFTCNGKLELEFFMRLWRYLNHFKAIFTDVDVDQNGFIG 631

  Fly    98 KTELKTALTSFGYRLSDHLIDVLLRKFDRFGRGTILFDDFIQCCIVLYTLTTAFRQ 153
            .:||:.|..|.|..:|...:.:||.::..: ...:.|:|:: ||:|  .|.:||::
Frog   632 LSELRKAAKSAGMAVSSDQLTILLLRYGDY-EMKLNFEDYL-CCMV--RLKSAFKR 683

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg-2	NP_001104459.2	EF-hand_7	16..71	CDD:290234	14/89 (16%)
		EFh	16..71	CDD:238008	14/89 (16%)
		EF-hand_7	82..139	CDD:290234	15/56 (27%)
		EFh	85..139	CDD:238008	15/53 (28%)
capn10l	XP_031758129.1	Peptidase_C2	43..365	CDD:395523
		Calpain_III	400..517	CDD:395848	4/14 (29%)
		EFh_PEF_CAPN13_14	541..708	CDD:320070	36/147 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910