DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12567 and Nudt2

DIOPT Version :9

Sequence 1:	NP_001015384.1	Gene:	CG12567 / 3355094	FlyBaseID:	FBgn0039958	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_079815.2	Gene:	Nudt2 / 66401	MGIID:	1913651	Length:	147	Species:	Mus musculus

Alignment Length:	130	Identity:	29/130 - (22%)
Similarity:	48/130 - (36%)	Gaps:	19/130 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 LQQRSNTKETW-PGKWDNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAGCVSFYFESR 219
            |.|.|:....| |.|      |.:..|....|||::|..||..|.:..: .::........:.:|
Mouse    28 LLQASDGIHHWTPPK------GHVDPGENDLETALRETREETGIEASQL-TIIEGFRRELNYVAR 85

  Fly   220 QGLFPNTEYVFDLELPLDFVPQNADGEVQAFELLTAKDCVERVFTSDFKTTSAPVVIDFLIRHGH 284
            |.  |.|...:..|:....|......|.||:..|..::..:.....:.|.|         ::.||
Mouse    86 QK--PKTVIYWLAEVKDYNVEIRLSQEHQAYRWLGLEEACQLAQFKEMKAT---------LQEGH 139

Fly 285 284
Mouse 140 139

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12567	NP_001015384.1	DUF4743	11..136	CDD:292538
CG12567	NP_001015384.1	Nudix_hydrolase_3	106..283	CDD:239648	27/127 (21%)
Nudt2	NP_079815.2	Ap4A_hydrolase_human_like	2..140	CDD:239520	29/130 (22%)
Nudt2	NP_079815.2	Nudix box	43..64		8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900