DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12567 and NUDT1

DIOPT Version :9

Sequence 1:	NP_001015384.1	Gene:	CG12567 / 3355094	FlyBaseID:	FBgn0039958	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_945187.1	Gene:	NUDT1 / 4521	HGNCID:	8048	Length:	179	Species:	Homo sapiens

Alignment Length:	130	Identity:	31/130 - (23%)
Similarity:	50/130 - (38%)	Gaps:	24/130 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 GKWDNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAGCVSFYF--------------ES 218
            |:| |..||.:..|..|::.|.:|..||:.:..|.   |...|.:.|.|              :|
Human    53 GRW-NGFGGKVQEGETIEDGARRELQEESGLTVDA---LHKVGQIVFEFVGEPELMDVHVFCTDS 113

  Fly   219 RQGLFPNTEYVFDLELPLDFVP--QNADGEVQAFELLTAKDCVERVFTSDFKTTSAPVVIDFLIR 281
            .||....::.:......||.:|  .....:...|.||..|    :.|...||......::|:.:|
Human   114 IQGTPVESDEMRPCWFQLDQIPFKDMWPDDSYWFPLLLQK----KKFHGYFKFQGQDTILDYTLR 174

Fly 282 281
Human 175 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12567	NP_001015384.1	DUF4743	11..136	CDD:292538
CG12567	NP_001015384.1	Nudix_hydrolase_3	106..283	CDD:239648	31/130 (24%)
NUDT1	NP_945187.1	MTH1	29..163	CDD:239519	29/117 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900