DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG12567 and NUDT19

DIOPT Version :9

Sequence 1:NP_001015384.1 Gene:CG12567 / 3355094 FlyBaseID:FBgn0039958 Length:349 Species:Drosophila melanogaster
Sequence 2:NP_001099040.1 Gene:NUDT19 / 390916 HGNCID:32036 Length:375 Species:Homo sapiens


Alignment Length:254 Identity:51/254 - (20%)
Similarity:84/254 - (33%) Gaps:98/254 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   102 PALQGWRDEYFEVKADCRALLKM--ERAATP-LFGVRKYGVDINGYVR----------------- 146
            |.|..|||   .|:.|.|..|::  ....|| ::.:..:...:..::|                 
Human   162 PGLASWRD---RVRQDPRHFLRLCAHLDCTPDIWALHNWSAWLTPFLRGTTRRFDTAFFLCCLRE 223

  Fly   147 ----HPTLGLCIWLQQRSN--------TKETW---PGKWDNMVGGGLSVGFGIKETAIKEAAEEA 196
                :|.|...:..|..|.        :||.|   |..::                 ::..|..|
Human   224 PPPVYPDLAEVVGYQWSSPSEATESFLSKEIWLPPPQFYE-----------------VRRLANFA 271

  Fly   197 SIPSDLVKNLVSAGCVSFYFESRQGLFPNTEYVFDLELPLDFVPQNADGEVQAF---EL-LTAKD 257
            |: |||.|     .|:....|.             ||..|..:...|||.|...   || |...|
Human   272 SL-SDLHK-----FCLGRALEG-------------LERWLPIILLTADGMVHLLPGDELYLEDSD 317

  Fly   258 CVERVFTSDFKTTSAPVVIDFLIRHGHITADDVVDFTQIVEL------LHVPLQSIYTY 310
            .:|.:.:::.||       :.:::.|.       .|.:||..      :||.:|..|.:
Human   318 FLENLMSTEKKT-------EEIMKEGK-------QFHRIVTYHRHLYDIHVTVQPKYKH 362

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG12567NP_001015384.1 DUF4743 11..136 CDD:292538 11/36 (31%)
Nudix_hydrolase_3 106..283 CDD:239648 41/215 (19%)
NUDT19NP_001099040.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 91..116
Nudix box 116..137
Microbody targeting signal. /evidence=ECO:0000255 373..375
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0494
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.