DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12567 and Nudt5

DIOPT Version :9

Sequence 1:	NP_001015384.1	Gene:	CG12567 / 3355094	FlyBaseID:	FBgn0039958	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001007734.1	Gene:	Nudt5 / 361274	RGDID:	1359284	Length:	219	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	33/186 - (17%)
Similarity:	53/186 - (28%)	Gaps:	60/186 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   146 RHPTLGLCIWLQQRSNTKETWPGKWDNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAG 210
            |.|..|.|:                 ....|.:..|...:..|::|..||.....|:.: ...|.
  Rat    84 RPPMGGYCL-----------------EFPAGLIEDGESPEAAALRELEEETGYKGDIAE-CSPAV 130

  Fly   211 CVSFYFESRQGLFPNTEYVFDLELPLDFV------PQNADGEVQAFELLTAKDCVERVFTSDFKT 269
            |:.      .||...|.:|..:.:..|..      |:..|||......|...|.:.|
  Rat   131 CMD------PGLSNCTTHVVTVTINGDDAGNVRPKPKPGDGEFVEVISLPKNDLLTR-------- 181

  Fly   270 TSAPVVIDFLIRHGHITADDVVDFTQIVELLHVPLQSIYTYKTRFEQSIKQPQFLP 325
                  :|.|.....:|.|                ..:|.|....:.:..:|..:|
  Rat   182 ------LDALGAEDRLTVD----------------ARVYAYALALKHANAKPFEVP 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12567	NP_001015384.1	DUF4743	11..136	CDD:292538
CG12567	NP_001015384.1	Nudix_hydrolase_3	106..283	CDD:239648	27/142 (19%)
Nudt5	NP_001007734.1	Substrate binding, shared with dimeric partner. /evidence=ECO:0000250\|UniProtKB:Q9UKK9	46..47
		ADPRase_NUDT5	60..207	CDD:239516	31/176 (18%)
		Nudix box	97..118		6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900