DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12567 and NUDT7

DIOPT Version :9

Sequence 1:	NP_001015384.1	Gene:	CG12567 / 3355094	FlyBaseID:	FBgn0039958	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_001099133.1	Gene:	NUDT7 / 283927	HGNCID:	8054	Length:	238	Species:	Homo sapiens

Alignment Length:	142	Identity:	35/142 - (24%)
Similarity:	53/142 - (37%)	Gaps:	44/142 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LSRLLILAQKFNNFYLSGIHKCDIRPFVVEGKQVGLIKSDVLKHL--EKYPEVFCIRACEQTKQG 70
            :|||.:..:...|..|... |..:|.:.:.||         ..||  .||..:..:.|    |:|
Human     1 MSRLGLPEEPVRNSLLDDA-KARLRKYDIGGK---------YSHLPYNKYSVLLPLVA----KEG 51

  Fly    71 LVELNPAFRDYNERTEQLEKVLRNLRSEGLFPALQGWRDEYFEVKADCRALLKMERAATPL---- 131
            .:.|.     :..|:|:    ||....|..||.  |.||.           ..|:.|||.|
Human    52 KLHLL-----FTVRSEK----LRRAPGEVCFPG--GKRDP-----------TDMDDAATALREAQ 94

  Fly   132 --FGVRKYGVDI 141
              .|:|.:.|::
Human    95 EEVGLRPHQVEV 106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12567	NP_001015384.1	DUF4743	11..136	CDD:292538	31/132 (23%)
CG12567	NP_001015384.1	Nudix_hydrolase_3	106..283	CDD:239648	11/42 (26%)
NUDT7	NP_001099133.1	CoAse	41..201	CDD:239518	22/92 (24%)
		Nudix box	77..98		7/31 (23%)
		Microbody targeting signal. /evidence=ECO:0000250	236..238
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900