DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12567 and ndx-2

DIOPT Version :9

Sequence 1:	NP_001015384.1	Gene:	CG12567 / 3355094	FlyBaseID:	FBgn0039958	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_503726.1	Gene:	ndx-2 / 189126	WormBaseID:	WBGene00003579	Length:	223	Species:	Caenorhabditis elegans

Alignment Length:	197	Identity:	41/197 - (20%)
Similarity:	66/197 - (33%)	Gaps:	60/197 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 QRSNTKETWPGKW--DNMVGGGLSVGFGIKETAIKEAAEEASIPSDLVKNLVSAGCVSFYFESR- 219
            |..|.:..|.|||  ...||.....|    :..:.::....:.|.:     .||..||.....|
Worm    30 QLFNQEVVWNGKWIQTRQVGFKTHTG----QVGVWQSVHRNTKPVE-----ASADGVSIIARVRK 85

  Fly   220 QGLFPNTEYV------------FDLELPLDFVP-------------QNADGEVQAFELLTAKDC- 258
            ||..    |:            ..||||...:.             :...|.|....::.:|.|
Worm    86 QGKL----YIVLVKQYRIPCGKLCLELPAGLIDAGETAQQAAIRELKEETGYVSGKVVMESKLCF 146

  Fly   259 VERVFTSDFKTTSAPVVIDFLIRHGHITAD--------DVVDFTQIVELLHVPLQSIYTYKTRFE 315
            ::...|.|   :...||:|       :..|        .|:|.|:.:|:|.|...::..|.|..:
Worm   147 LDPGLTDD---SQCLVVVD-------VDGDAPENQNPVQVLDSTESIEVLLVEQSALMAYVTNLD 201

  Fly   316 QS 317
            .|
Worm   202 SS 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12567	NP_001015384.1	DUF4743	11..136	CDD:292538
CG12567	NP_001015384.1	Nudix_hydrolase_3	106..283	CDD:239648	31/153 (20%)
ndx-2	NP_503726.1	ADPRase_NUDT5	75..221	CDD:239516	29/143 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900