DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG40470 and Rnpep

DIOPT Version :9

Sequence 1:	NP_001036635.1	Gene:	CG40470 / 3355093	FlyBaseID:	FBgn0058470	Length:	941	Species:	Drosophila melanogaster
Sequence 2:	NP_112359.2	Gene:	Rnpep / 81761	RGDID:	621137	Length:	650	Species:	Rattus norvegicus

Alignment Length:	319	Identity:	53/319 - (16%)
Similarity:	115/319 - (36%)	Gaps:	79/319 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   195 RRLFPCFDEPGIKVPFNVSIARPKGYITLFNTPLHNTINHPKLRSYSLDFFHTTAPMSTHAFGFV 259
            |..|||||.|.:|..::..:..|.|:..:.:....      :.|..:..||....|:.::.....
  Rat   176 RAFFPCFDTPAVKCTYSALVEVPDGFTAVMSASTW------ERRGPNKFFFQMNQPIPSYLIALA 234

  Fly   260 ILKLHMWNEHKIVKSSDI-PAINIWSNN-LSSTNLLDIQNKLNVAHTTIQHFFNIPLPLTKLDVI 322
            |..|         .|::: |...:|:.. |......:....:.....|.:..|. |....:.|::
  Rat   235 IGDL---------ASAEVGPRSRVWAEPCLIEAAKEEYNGVIEEFLATGEKLFG-PYVWGRYDLL 289

  Fly   323 AIPSLATLPF--------ISASGILIARESEILKKDVFEISRELIYQWIGIWITPEWWTDANVNK 379
            .:|  .:.||        ...:..|:|.:..:....:.|||    :.|.|..:|...|.:..:|:
  Rat   290 FMP--PSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEIS----HSWFGNLVTNANWGEFWLNE 348

  Fly   380 ALISFIASEIVFEINGGIEFNGKYPMTILYSLYY---------ELSKRYPNSHITGIKHEFASIK 435
            ....:....|               .|||:...|         .|.:::.:  ::|.::....::
  Rat   349 GFTMYAQRRI---------------STILFGAAYTCLEAATGRALLRQHMD--VSGEENPLNKLR 396

  Fly   436 VQL--------------------IIRMLSLTVG-KYTFRLGIQSFICDYKFKTYKSSDF 473
            |::                    .:..|:..|| :..|...:::::.::||::..:.||
  Rat   397 VKIEPGVDPDDTYNETPYEKGYCFVSYLAHLVGDQEQFDKFLKAYVDEFKFQSILAEDF 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG40470	NP_001036635.1	GluZincin	60..503	CDD:301352	53/319 (17%)
CG40470	NP_001036635.1	ERAP1_C	584..906	CDD:288671
Rnpep	NP_112359.2	M1_LTA4H	24..484	CDD:341062	53/319 (17%)
		Substrate binding. /evidence=ECO:0000250	298..302		0/3 (0%)
		Leuk-A4-hydro_C	530..645	CDD:401171
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900