Protein Alignment CG40470 and CG4467

DIOPT Version :9

• Sequence 1: NP_001036635.1
• Gene: CG40470 / 3355093
• FlyBaseID: FBgn0058470
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Alignment Length: 1077
• Identity: 220/1077 - (20%)
• Similarity: 393/1077 - (36%)
• Gaps: 291/1077 - (27%)

  Fly    50 EVRLPKEVLPLSYEVLIEPHMDNQNFEGSIRMHLRWIGDSKKVYFHAHDTLLIDVSQINLTTLNM 114
            |..||..|.||.|.|.|.|::...:.:|.:.:.|....::..:..|..|   ::|::..:.|
  Fly   135 EKMLPTSVRPLRYMVTIHPNLTTLDVKGQVTIDLHVEKETNFIVLHIQD---LNVTEKAIVT--- 193

  Fly   115 GDGTLDKNVIILRGVRLPRKPVFVLYLKDKIKKGSECLLDIYFQGNISETEEGLFRSYYTNSGND 179
             .|.....:.|::.:..|.:....:.:|:::||.|...|::.:...::...||.:...| .|.|.
  Fly   194 -PGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQY-ESSNG 256

  Fly   180 GEEIYLATNLKPNNARRLFPCFDEPGIKVPFNVSIARPKGYITLFNTPLHNT------INHPKLR 238
            .|.:..||..:||.|||.|||||||.::.||.:|:.|.:.:|.|.|:.:|.|      :....||
  Fly   257 VERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLR 321

  Fly   239 SYSLDFFHTTAPMSTHAFGFVI----------------------------LKLHMWNEHKIVKSS 275
                |.|..|.|:...|..:|:                            .|....|.:..:|..
  Fly   322 ----DDFIETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGK 382

  Fly   276 DIPAINI---------------------------WSNNLSS----TNLLDIQNKLN--------- 300
            :.|..||                           |..||:.    :||..:.....
  Fly   383 NPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPSNLTSLSQSTGSSIKRAPSY 447

  Fly   301 --------------VAHTT------IQHFFNIPLPLTKLDVIAIPSLATLPFISASGILIAR--- 342
                          :.||:      :|.:.:|..||||:|.:|:||| ....||:.|::..:
  Fly   448 TFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSL-DRNMISSLGLVTLKTSF 511

  Fly   343 -------ESEILKKDVFEISRELIYQWIG----------IWITPEWWTDANVNKALISFIASEIV 390
                   .||..:.....|:..::.|:.|          :|:    |      :.||.::.
  Fly   512 LTDPSSITSEQYQFSALRIAEAMVRQFFGGITSRKVLKDVWL----W------EGLIQYLG---- 562

  Fly   391 FEINGGIEFNGKYPMTILYSLYYELSK------RYPNSHITGIKH-----EFASIKVQLIIRMLS 444
              |:........:|:..:|.|....:.      :..:|.:.|..|     ||...|...|..||.
  Fly   563 --IHALAPLQETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFFVQKTAAIFSMLH 625

  Fly   445 LTVGKYTFRLGIQSFICDYKFKTYKSSDFWNAITTQAKADNSLDSDLSILSIAESWLEHSRLPLV 509
            ..:|:..||..:.||:...:|:|.:.:|.|...|.:|....::...:::      |......||:
  Fly   626 TAIGEDRFRGCLGSFLKVNRFRTAEPTDLWTICTKKANGSKNIKDMMTL------WTHQPGFPLL 684

  Fly   510 TIIR-----------------------DYDSETAIVQQKVYLRERLH--DVPD------------ 537
            |:.:                       .||...       |.:..|:  |:|.
  Fly   685 TVTKMGNSISISQRPFRPAEFLAIHDDSYDGNN-------YNKTTLNATDMPSTVATTTQGSKHK 742

  Fly   538 -QDNMLWWIPIALKRQDSLSFV----NTGSFKWMNKTRQMLISNLPSKNMFIIVNEEEIGPFPVN 597
             ..:|.|..|:        ::|    |.....||....  :..|:|....:|.||..:.|.:.|.
  Fly   743 VAPHMKWIFPV--------TYVTDINNVSETLWMQNVD--VTFNVPENVKWIKVNAIQNGYYRVV 797

  Fly   598 YDDNNWNMLSKYLRTEEKRESIPVYT---RAKLLHDAWNLAYAGELNFSTALNVTLFLKYE---- 655
            |:|:||..|.:.|.....|     :|   |..:|.||:.|.:|..|.....:|:..:|..|
  Fly   798 YNDDNWASLIEELAANPNR-----FTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYG 857

  Fly   656 ------------RNHIVWSPVFTFLDQVGKRLEKSSINKKFEL-----YIIELLAPLYEYLGTAH 703
                        |..:.:|..|..|.:..| ::.|::.:|...     ....||.|  |.|..:.
  Fly   858 PMALALRHLEKWRRILKYSECFLMLSEFIK-MKISTVMEKVGWSDDGDVATRLLRP--EVLLASV 919

  Fly   704 FNEDI-NITELRKLTTSFLCKAGYF------PCFKEARRAFNIWINSSFPNFETPVPNEYICSIF 761
            ..||| :||:.:.:...:|    |:      |..:|.....:|            :..|||
  Fly   920 LWEDIDSITKAKNMLNQYL----YYNGTAIPPNLREVVYTGSI------------LSGEYI---- 964

  Fly   762 KWGSMKEWMFGLDRLCEFPKSRIQSDRTHLLKMLAGCPAQRDKIFILLELAILKNISIFSDTDKM 826
            .|....|....|.|..|....|:|     ||:.|.     |.| ...|:..:|.::::....:.:
  Fly   965 YWQHCWERFVNLQRTSETFVERMQ-----LLRALG-----RTK-DAWLQNRLLSHVTMLPTEEVV 1018

  Fly   827 LIISTVTSRSIGYTTLLDFLSNNWDDIHHKFYNNTNIWTKLISSATGMFSTQEGYDLVKKFYDEH 891
            .::..:.....|......||...|.::..:....|..:.|:||:.|...:|:..||.:|... ..
  Fly  1019 QVLKAIAGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGATKFDYDELKSLV-HR 1082

  Fly   892 YGHFGRAQHIIEKSLRNIKEGIQWSKQNIPVIEEWID 928
            :|. |....::..:|.::...::|..::...:.:|::
  Fly  1083 FGR-GHGMSVLNMTLSSVASNVEWVARSQTSLYKWVE 1118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40470	NP_001036635.1	GluZincin	60..503	CDD:301352	117/567 (21%)
		ERAP1_C	584..906	CDD:288671	77/352 (22%)
CG4467	NP_001036747.1	Peptidase_M1	138..593	CDD:279741	100/483 (21%)
		GluZincin	145..682	CDD:301352	117/571 (20%)
		ERAP1_C	784..1078	CDD:288671	74/332 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0308
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920