Protein Alignment CG40470 and erap1b

DIOPT Version :10

• Sequence 1: NP_001036635.1
• Gene: CG40470 / 3355093
• FlyBaseID: FBgn0058470
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: NP_956500.2
• Gene: erap1b / 393175
• ZFINID: ZDB-GENE-040426-934
• Length: 963
• Species: Danio rerio
• Alignment Length: 1022
• Identity: 242/1022 - (23%)
• Similarity: 444/1022 - (43%)
• Gaps: 175/1022 - (17%)

  Fly    16 MASGTRTLFILTILLTAPGLEAFVNDFSSLHVIS---------EVRLPKEVLPLSYEVLIEPHMD 71
            ||:.||...:|.:::....|.|.|....:...||         ::|||..:.||.|.:||.|::.
Zfish     1 MATMTRLPVLLNLIVLPIHLWAAVTPEPTSFPISSSGEPFPWNKMRLPDTISPLHYNLLIHPNLT 65

  Fly    72 NQNFEGSIRMHLRWIGDSKKVYFHAHDTLLIDVSQINLTTLNMGDGTLDKNVIILRGVRLPRKPV 136
            :.:|.||:::.:..:.|:|.:..|:.:   :.:|...|         ||.|:...:.:::...|.
Zfish    66 SLDFTGSVQIQIEVLQDTKTIILHSKN---LQISSARL---------LDANIAQQQPLKVLEYPY 118

  Fly   137 F--VLYLKDK--IKKGSECLLDIYFQGNISETEEGLFRSYYTNSGNDGEEIYLATNLKPNNARRL 197
            |  :..:.||  :|:|....::::|..|:||:..|.::|.|..|..| ..:..:|..:..:||..
Zfish   119 FQQIALVSDKALLKRGHVYSVELHFAANLSESFHGFYKSTYRTSKGD-VRVVASTQFEATSARAA 182

  Fly   198 FPCFDEPGIKVPFNVSIARPKGYITLFNTPLHNTINHPKLRSYSL------DFFHTTAPMSTHAF 256
            |||||||..|..|:|.|.|...:|.|.|.        ||||:..|      |.|..:..|||:..
Zfish   183 FPCFDEPAFKANFSVQIRREAKHIALSNM--------PKLRTLELKNGLFEDQFDVSVKMSTYLV 239

  Fly   257 GFVILKLHMWNEHKIVKSSDIPAINIWSNNLSSTNLLDIQNKLNVAHTTI----------QHFFN 311
            .:::              ||..:|:..|.:....::..:..|::.|...:          ..:|:
Zfish   240 AYIV--------------SDFLSISKTSQHGVQISVYAVPEKIDQAEFALDAAVKLLDFYDDYFD 290

  Fly   312 IPLPLTKLD--------------VIAIPSLATLP-FISAS----GILIARESEIL----KKDVFE 353
            ||.||.|.:              :|....||.:| |.|.:    |:...|||.:|    |....:
Zfish   291 IPYPLPKQEKPTIKHAKEEFSVYIICFVDLAAIPDFQSGAMENWGLTTYRESALLFDPHKSSASD 355

  Fly   354 -------ISRELIYQWIGIWITPEWWTDANVNKALISFIASEIVFEINGGIE----FNGKYPMTI 407
                   |:.||.:||.|..:|.:||.|..:|:....|:....|...|..::    |.||
Zfish   356 KLGITMIIAHELAHQWFGNLVTMQWWNDLWLNEGFAKFMEFVSVNITNPELQVEDYFLGK----- 415

  Fly   408 LYSLYYE------LSKRYPNS----HITGIKHEFASI---KVQLIIRMLSLTVGKYTFRLGIQSF 459
                .:|      ||..:|.|    :...|:..|..:   |...|:.||...:....|:|||..:
Zfish   416 ----CFEAMEVDSLSSSHPVSTPVENPAQIQEMFDDVSYDKGACILNMLREFLTPKIFKLGIVKY 476

  Fly   460 ICDYKFKTYKSSDFWNAITT----------QAKADNSL--------------DSDLSILSIAESW 500
            :..|.::...:|:.|.::|.          :.|.|.|.              :.:|.:.::.|:|
Zfish   477 LKHYSYQNTVNSNLWESLTNVCDSDGLDEGRLKGDESCRHSASNTGASKWHSEDELDVKAMMETW 541

  Fly   501 LEHSRLPLVTIIRDYDSETAIVQQKVYLRERLHDVPDQDNMLWWIPIALKRQDSLSFVNTGSFKW 565
            ......||:||.  .......:.|:.||:.  .|:....:.||.:|:.....||     |...::
Zfish   542 TLQEGFPLITIA--VKGREVRLSQERYLKS--DDLSQTSSFLWQVPLTYITSDS-----TTVHRF 597

  Fly   566 MNKTRQMLISNLPSKNMFIIVNEEEIGPFPVNYDDNNWNMLSKYLRTEEKRESIPVYTRAKLLHD 630
            :.||:..:: .||.:..:|..|.:..|.:.|:|:.:.|:.|...|:  ....::....||.|:::
Zfish   598 LLKTKTDVL-YLPEEVDWIKFNVDMSGYYIVHYEGSGWDDLITLLK--HNHTALSSNDRASLINN 659

  Fly   631 AWNLAYAGELNFSTALNVTLFLKYERNHIVWSPVFTFLDQVGKRLEKS---SINKKFELYIIELL 692
            |:.|...|:|....||::||:|..|...:..:..|..|..:.|.:||.   .:..:.:.||::|.
Zfish   660 AFQLVSVGKLPLDKALDLTLYLSKETEIMPVTQGFNELVPLYKLMEKRDMVELENQMKGYILQLF 724

  Fly   693 APLYEYLGTAHFNEDINITE--LRKLTTSFLCKAGYFPCFKEARRAFNIWINSSFPNFETPVPNE 755
            ..|.|   ...:.::.:::|  ||.....|.|..|:.||...|.:.||:|.:|   :....:||:
Zfish   725 QKLIE---QQLWTDEGSVSERMLRSYLLLFGCVRGHPPCVSNATQLFNLWRDS---DGNMSLPND 783

  Fly   756 YICSIFKWGSMKE--WMFGLDRLCEFPKSRIQSDRTHLLKMLAGCPAQRDKIFILLELAILKNIS 818
            ...::|..|:..|  |.|..::   :.:|...|.::.:.:.|...|... |:..::|.::  ...
Zfish   784 VTMAVFSVGARTEDGWDFLFEK---YKESMYVSMKSRIKQALMTSPLDH-KLKWMMEQSL--EGE 842

  Fly   819 IFSDTDKMLIISTVTSRSIGYTTLLDFLSNNWDDIHHKFYNNTNIWTKLISSATGMFSTQEGYDL 883
            :....|...::::|:.....|....|||..|||.:..||...::....::...|..:||:|....
Zfish   843 LIKTQDLPYVVTSVSRNPKAYKHAWDFLQANWDSLIKKFDLGSHSIAHMVVGVTNQYSTREMLAE 907

  Fly   884 VKKFYDEHYGHFGRAQHIIEKSLRNIKEGIQWSKQNIPVIEEWIDHY 930
            |:.|:.......|.....|::::.||:|.|:|..:|:|:::.|:..|
Zfish   908 VRNFFSLLQPETGAELRCIQQAVENIEENIRWMDKNLPLLKAWLHRY 954

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40470	NP_001036635.1	GluZincin	60..502	CDD:472708	125/532 (23%)
		ERAP1_C	583..910	CDD:463368	77/333 (23%)
erap1b	NP_956500.2	M1_APN-Q_like	54..543	CDD:341064	125/532 (23%)
		ERAP1_C	614..934	CDD:463368	77/333 (23%)