Protein Alignment CG40470 and LOC1277402

DIOPT Version :10

• Sequence 1: NP_001036635.1
• Gene: CG40470 / 3355093
• FlyBaseID: FBgn0058470
• Length: 941
• Species: Drosophila melanogaster
• Sequence 2: XP_061507132.1
• Gene: LOC1277402 / 1277402
• VectorBaseID: AGAMI1_008618
• Length: 979
• Species: Anopheles gambiae
• Alignment Length: 965
• Identity: 242/965 - (25%)
• Similarity: 446/965 - (46%)
• Gaps: 86/965 - (8%)

  Fly    16 MASGTRTLFILTILLTAPGLEAFVNDFSSLHVISEVRLPKEVLPLSYEVLIEPHMDNQN---FEG 77
            ||.|..::.:..|..|..|:.  |.|....:  |..||||.:.|..|.:.:..|:.::.   |.|
Mosquito    25 MAMGRSSMLLAVIAATIIGVT--VGDTGVPY--SGYRLPKSITPEHYNLRVYTHLGDERGFIFYG 85

  Fly    78 SIRMHLRWIGDSKKVYFHAHDTLLIDVSQINLTTLNMGDGTLDKNVIILRGVRLPRKPVFV-LYL 141
            .:.|.|....|::.:..|:.: |.:....|:|..|... |..:.:.|.::.|:..::..|| |.:
Mosquito    86 QVAMRLICHEDTENIVLHSKN-LTLPEQGISLRELGSA-GQQNGSAIAIKSVQYAKEHDFVILNV 148

  Fly   142 KDKIKKGSECLLDIYFQGNISETEEGLFRSYYTNSGNDGEEIYLA-TNLKPNNARRLFPCFDEPG 205
            ...::||:...|.:.|:..:.....|.:||.|.:..:. ::|:|| |..:|..||:.|||||||.
Mosquito   149 ATVLRKGNRYELVVPFESALGTGLLGYYRSSYVDKASK-QKIWLAVTQFEPTYARQAFPCFDEPE 212

  Fly   206 IKVPFNVSIARPKGYITLFNTPLHNTINHPKLRSYSLDFFHTTAPMSTHAFGFVILKLHMWNEHK 270
            :|..|::::|..:.|:.|.|.|::::.....:..:.:|.|.||.||||:...:.:.... :.|..
Mosquito   213 MKATFDIALAHDERYVALSNMPVNSSAPVDGMPGWVMDVFGTTVPMSTYLVAYTVNDFE-YREAM 276

  Fly   271 IVKSSDIPAINIWSNNLSSTNLLDIQNKLNVAHTTI-QHFFNIPLPLTKLDVIAIPSLATLPFIS 334
            ..:..|: ...||:.. .:...:|...::....|.. :.:|....||.|:|:||||..|: ..:.
Mosquito   277 AAEEGDV-LFKIWARR-DAIEQVDYAREIGPKVTRFYEDYFQQKFPLPKIDMIAIPDFAS-GAME 338

  Fly   335 ASGILIARESEIL----------KKDVFE-ISRELIYQWIGIWITPEWWTDANVNKALISFIASE 388
            ..|::..||:.:|          |..|.. |:.||.:||.|..:|..||||..:|:...:::||.
Mosquito   339 NWGLITYRETALLYHPNVSTASNKHRVASVIAHELAHQWFGNLVTMRWWTDLWLNEGFATYVASL 403

  Fly   389 IVFEINGGIEF---------NGKYPMTILYSLYYELSKRYPNS----HITGIKHEFASI---KVQ 437
                   |:::         ......|:....:..|...:|.|    |...|...|.:|   |..
Mosquito   404 -------GVDYLHPEWHSLEEESVSNTLDIFKFDALQSSHPISVEIGHPNQISQIFDAISYEKGS 461

  Fly   438 LIIRMLSLTVGKYTFRLGIQSFICDYKFKTYKSSDFWNAITTQAKADNSLDSDLSILSIAESWLE 502
            ::|||:.|.:.:.|||.|:..::..:.:...:..:.|.|:|.:|.|:..|...:.:..:.:||..
Mosquito   462 IVIRMMHLFLDEETFRDGVGRYLRRHAYGNAEQDNLWAALTEEAHANGVLPDHIDVKKVMDSWTL 526

  Fly   503 HSRLPLVTIIRDYDSETAIVQQKVYLRERLHDV-PDQD--NMLWWIPIALKRQDSLSFVNTGSFK 564
            .:..|::|:.|:||:.||.|.|..::..   || ||.:  :..||||:.......:.|.:|....
Mosquito   527 QTGYPIITVTRNYDANTAEVTQMRFISS---DVRPDSNVTDYCWWIPLTYTTAKQIDFNDTLPKA 588

  Fly   565 WM---------NKTRQMLISNLPSKNMFIIVNEEEIGPFPVNYDDNNWNMLSKYLRTEEKRESIP 620
            ||         ::....|:.:||..:.::|.|.|..|.:.|.||..|:.::...|......| |.
Mosquito   589 WMACSGEPKGSHQQEAKLLEDLPDGDQWVIFNVELAGLYKVRYDRRNYQLIIAQLNGPRFGE-IG 652

  Fly   621 VYTRAKLLHDAWNLAYAGELNFSTALNVTLFLKYERNHIVWSPVFTFLDQVGKRLEKSSINKKFE 685
            :..||:|:.||.:||:.|:.|:..|..:..:|:.|..:|.|....|.|:.:.:.|:::.:...|.
Mosquito   653 LLNRAQLIDDAMDLAWTGQQNYGIAFAMLNYLRQETQYIPWKSALTNLNNINRILKRTPLYGVFR 717

  Fly   686 LYIIELLAPLYEYLGTAHFNEDINITE----LRKLT--TSFLCKAGYFPCFKEARRAFNIWINSS 744
            .|:..:|.|:||.|..  ||.....||    ::::|  .|:.|:.....|...:...|..|:|.|
Mosquito   718 SYVQYILEPIYEQLDI--FNGSRATTERLDGIKQITLIASWACRFEVGDCVNRSVELFARWMNES 780

  Fly   745 FPNFETPVPNE----YICSIFKWGSMKEWMFGLDRLCEFPKSRIQSDRTHLLKMLAGCPAQRDKI 805
            .|:.:.|||..    ..|:..:.|...:|.|   ....:.:|.:.:::..::..|| |..:...:
Mosquito   781 SPDTDNPVPVNLRPVVYCNAIRRGDEAQWHF---LWLRYLQSNVGAEKIMIIGSLA-CTREVRLV 841

  Fly   806 FILLELAILKNISIFSDTDKMLIISTVTSRSIGYTTLLDFLSNNWDDIHHKFYNNTNIWTKLISS 870
            ...|:.: |.:.|.....|..::.|.|:....|:.....|.....|||::....:|:..::.|..
Mosquito   842 ERFLQWS-LNSTSGVRKQDATILFSGVSRNDAGFAAAKKFFLERADDIYNYLSPDTSRLSRYIKP 905

  Fly   871 -ATGMFSTQEGYDLVKKFYDEHYGHFGRAQHIIEKSLRNIKEGIQWSKQNIPVIE 924
             |..|||::|..:|. ...::....|.:|...::::|...:...:|||.||..:|
Mosquito   906 LAEQMFSSEELQELT-DLIEQKAPIFEKANQGVKQALETAQTNNRWSKVNIDKME 959

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG40470	NP_001036635.1	GluZincin	60..502	CDD:472708	117/474 (25%)
		ERAP1_C	583..910	CDD:463368	81/337 (24%)
LOC1277402	XP_061507132.1	None