DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snap25 and SNAP30

DIOPT Version :9

Sequence 1:	NP_001036641.1	Gene:	Snap25 / 3355084	FlyBaseID:	FBgn0011288	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001318998.1	Gene:	SNAP30 / 837948	AraportID:	AT1G13890	Length:	263	Species:	Arabidopsis thaliana

Alignment Length:	218	Identity:	61/218 - (27%)
Similarity:	103/218 - (47%)	Gaps:	45/218 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMREAEK 83
            |||:..|...|:|:.:.....|.:.|:.:..|.|||..|..||||::|..|....::.|:...||
plant    64 EELEKYAVYKAEETTKGVNNCLKIAEDIRSDGARTLEMLHQQGEQINRTHEMAVDMDKDLSRGEK 128

  Fly    84 ---NLSGM----------EKCCGICVL---PCNKSQSFKEDD-----GTWKGNDDGKVVNNQP-- 125
               ||.||          :...|..:.   |..||::.||:.     |. ||....:...:||
plant   129 LLNNLGGMFSKPWKPKKTKNITGPMITPDKPSKKSENHKEEREKLGLGA-KGRSSSQPALDQPTN 192

  Fly   126 --QRVMDDRNGMMAQAGYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDR 188
              |:|..::                |::|   :.:..::.::|:|::||:|||||::.||:.:|.
plant   193 ALQKVEQEK----------------AKQD---DGLSDLSDILGDLKSMAVDMGSEIDKQNKALDH 238

  Fly   189 INRKGESNEARIAVANQRAHQLL 211
            :....:...:|:..|||||..||
plant   239 LGDDVDELNSRVQGANQRARHLL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap25	NP_001036641.1	SNARE_SNAP25N_23N	28..87	CDD:277242	20/61 (33%)
		SNAP-25	98..149	CDD:279208	12/59 (20%)
		SNARE_SNAP25C	151..209	CDD:277238	19/57 (33%)
SNAP30	NP_001318998.1	SNARE_SNAP25N_23N_29N_SEC9N	68..132	CDD:277214	19/63 (30%)
SNAP30	NP_001318998.1	SNARE_Qc	201..259	CDD:277194	20/76 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2314
OMA	1	1.010	-	-		QHG60093
OrthoDB	1	1.010	-	-		D1197028at2759
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	1	1.000	-	-		mtm952
orthoMCL	1	0.900	-	-		OOG6_102919
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840