DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snap25 and SNAP33

DIOPT Version :9

Sequence 1:	NP_001036641.1	Gene:	Snap25 / 3355084	FlyBaseID:	FBgn0011288	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001332102.1	Gene:	SNAP33 / 836242	AraportID:	AT5G61210	Length:	300	Species:	Arabidopsis thaliana

Alignment Length:	213	Identity:	58/213 - (27%)
Similarity:	104/213 - (48%)	Gaps:	21/213 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VPKTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINAD 77
            :....::||:..|...|:|:.:|.:..|.:.|:.:....||||.|.|||||:.|......:|:.|
plant    93 IENQSVQELEGYAVYKAEETTKSVQGCLKVAEDIRSDATRTLVMLHDQGEQITRTHHKAVEIDHD 157

  Fly    78 MREAEK---NLSGM-------EKCCGICVLPCNKSQSFKEDDGTWKGNDDGK----VVNNQPQRV 128
            :...||   :|.||       :|     ..|.|.....::|..|.:.|...|    .:|:.|:..
plant   158 LSRGEKLLGSLGGMFSKTWKPKK-----TRPINGPVVTRDDSPTRRVNHLEKREKLGLNSAPRGQ 217

  Fly   129 MDDRNGMMAQAGYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKG 193
            ...|..:...|....|:  :..:.:.::.:..::.::|.|:|||:|||||:|.||:.:|.::...
plant   218 SRTREPLPESADAYQRV--EMEKAKQDDGLSDLSDILGELKNMAVDMGSEIEKQNKGLDHLHDDV 280

  Fly   194 ESNEARIAVANQRAHQLL 211
            :....|:..:|||..:||
plant   281 DELNFRVQQSNQRGRRLL 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap25	NP_001036641.1	SNARE_SNAP25N_23N	28..87	CDD:277242	21/61 (34%)
		SNAP-25	98..149	CDD:279208	11/54 (20%)
		SNARE_SNAP25C	151..209	CDD:277238	18/57 (32%)
SNAP33	NP_001332102.1	SNARE_SNAP25N_23N_29N_SEC9N	104..167	CDD:277214	21/62 (34%)
SNAP33	NP_001332102.1	SNARE_Qc	238..296	CDD:277194	18/57 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	87	1.000	Inparanoid score	I2314
OMA	1	1.010	-	-		QHG60093
OrthoDB	1	1.010	-	-		D1197028at2759
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	1	1.000	-	-		mtm952
orthoMCL	1	0.900	-	-		OOG6_102919
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840