DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snap25 and snap23.2

DIOPT Version :9

Sequence 1:	NP_001036641.1	Gene:	Snap25 / 3355084	FlyBaseID:	FBgn0011288	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001032194.2	Gene:	snap23.2 / 641321	ZFINID:	ZDB-GENE-051030-75	Length:	200	Species:	Danio rerio

Alignment Length:	200	Identity:	61/200 - (30%)
Similarity:	102/200 - (51%)	Gaps:	17/200 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMREAEK 83
            |::.|.|..|.:.|||||||:..:.||....|..|:..||:|||:|..::..:..||.|:::|:.
Zfish     4 EQITIKANHVTNASLESTRRIAQMTEECLNMGAETMTMLDEQGEKLHNVKRELGHINQDIKQAQA 68

  Fly    84 NLSGMEKCC--GIC--VLPCNKSQSFKEDDGTWKGNDDGKVVNNQPQRVMDDRNGMMAQA----- 139
            ||:.:....  ..|  :.|..:..:.|:..   |..:...|.:..|..|   :.|....|
Zfish    69 NLNKLSSWTWKSFCSRLKPTKRESTSKQAS---KPKERQNVASCHPAAV---QKGQAVSAESTAP 127

  Fly   140 --GYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAV 202
              .||.|||||.||:|||:|:.::...|..:|:..|::.::|:.||:.|..|....:.....:|.
Zfish   128 SGPYITRITNDERENEMEDNLTKLGHCIKIIRDQTLEINNKLDEQNKTIQDIQNDVDQANDDVAT 192

  Fly   203 ANQRA 207
            ||::|
Zfish   193 ANKQA 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap25	NP_001036641.1	SNARE_SNAP25N_23N	28..87	CDD:277242	24/58 (41%)
		SNAP-25	98..149	CDD:279208	14/57 (25%)
		SNARE_SNAP25C	151..209	CDD:277238	16/56 (29%)
snap23.2	NP_001032194.2	SNARE	9..72	CDD:304603	25/62 (40%)
		SNAP-25	82..138	CDD:279208	14/61 (23%)
		SNARE_Qc	142..199	CDD:277194	15/55 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592303
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1197028at2759
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.810