DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snap25 and zgc:101731

DIOPT Version :9

Sequence 1:	NP_001036641.1	Gene:	Snap25 / 3355084	FlyBaseID:	FBgn0011288	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_001020729.1	Gene:	zgc:101731 / 447892	ZFINID:	ZDB-GENE-040912-57	Length:	209	Species:	Danio rerio

Alignment Length:	201	Identity:	120/201 - (59%)
Similarity:	151/201 - (75%)	Gaps:	5/201 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMR 79
            ::|:||||..|..:.|||||.||.|..|.||||:|||||||.||:|||||||||||:||||.||:
Zfish     8 RSEVEELQKKANQMTDESLEVTRNMKLLLEESKDAGIRTLVMLDEQGEQLDRIEEGLDQINKDMK 72

  Fly    80 EAEKNLSGMEKCCGICVLPCNKSQSFKEDDGTWK---GNDDGKVVNNQP-QRVMDDRNGMMAQAG 140
            ||||||:.|..|||:|:.||.|.:.| |..|.:|   ||:...||::|| .||:|:|..|....|
Zfish    73 EAEKNLTDMAMCCGLCIWPCTKLKDF-EASGAYKKVWGNNQDGVVSSQPSSRVVDEREKMTMSGG 136

  Fly   141 YIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAVANQ 205
            ||.|:||||||||||||:.||.:::||||:||||||:|::.||.||:||..|...||:||..|||
Zfish   137 YIRRVTNDAREDEMEENLAQVGSILGNLRSMALDMGNEIDTQNVQIERIQSKAVVNESRINEANQ 201

  Fly   206 RAHQLL 211
            ||.:|:
Zfish   202 RATKLI 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap25	NP_001036641.1	SNARE_SNAP25N_23N	28..87	CDD:277242	45/58 (78%)
		SNAP-25	98..149	CDD:279208	24/54 (44%)
		SNARE_SNAP25C	151..209	CDD:277238	36/57 (63%)
zgc:101731	NP_001020729.1	SNARE_SNAP25N	10..81	CDD:277247	51/70 (73%)
		SNAP-25	91..145	CDD:279208	24/54 (44%)
		SNARE_SNAP23C	147..205	CDD:277237	36/57 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592305
Domainoid	1	1.000	119	1.000	Domainoid score	I5745
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H83182
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3416
OMA	1	1.010	-	-		QHG60093
OrthoDB	1	1.010	-	-		D1197028at2759
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	1	1.000	-	-		mtm6608
orthoMCL	1	0.900	-	-		OOG6_102919
Panther	1	1.100	-	-	LDO	PTHR19305
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1125
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770