DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snap25 and snap25a

DIOPT Version :9

Sequence 1:	NP_001036641.1	Gene:	Snap25 / 3355084	FlyBaseID:	FBgn0011288	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_571510.1	Gene:	snap25a / 30712	ZFINID:	ZDB-GENE-980526-468	Length:	204	Species:	Danio rerio

Alignment Length:	197	Identity:	118/197 - (59%)
Similarity:	149/197 - (75%)	Gaps:	3/197 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEEGMDQINADMR 79
            :.||.::|..|..:||||||||||||.|.||||:|||||||.||:|||||:||||||||||.||:
Zfish     8 RNELADMQQRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMK 72

  Fly    80 EAEKNLSGMEKCCGICVLPCNKSQSFKEDDGTWKGNDDGKVVNNQPQRVMDDRNGMMAQAGYIGR 144
            :|||||:.:.|.||:|..||||.:|....  .|..|.|| ||.:||.||:|:|..|....|:|.|
Zfish    73 DAEKNLNDLGKFCGLCSCPCNKMKSGASK--AWGNNQDG-VVASQPARVVDEREQMAISGGFIRR 134

  Fly   145 ITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQIDRINRKGESNEARIAVANQRAHQ 209
            :|:||||:||:||:.||..:|||||:||||||:|::.||||||||..|.:||:.|...|||||.:
Zfish   135 VTDDARENEMDENLEQVGGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRFDEANQRATK 199

  Fly   210 LL 211
            :|
Zfish   200 ML 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snap25	NP_001036641.1	SNARE_SNAP25N_23N	28..87	CDD:277242	48/58 (83%)
		SNAP-25	98..149	CDD:279208	22/50 (44%)
		SNARE_SNAP25C	151..209	CDD:277238	36/57 (63%)
snap25a	NP_571510.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..25		6/16 (38%)
		SNARE_SNAP25N	10..82	CDD:277247	52/71 (73%)
		SNAP-25	91..139	CDD:279208	22/50 (44%)
		SNARE_SNAP25C	141..199	CDD:277238	36/57 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592307
Domainoid	1	1.000	119	1.000	Domainoid score	I5745
eggNOG	1	0.900	-	-		E1_KOG3065
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3416
OMA	1	1.010	-	-		QHG60093
OrthoDB	1	1.010	-	-		D1197028at2759
OrthoFinder	1	1.000	-	-		FOG0000822
OrthoInspector	1	1.000	-	-		mtm6608
orthoMCL	1	0.900	-	-		OOG6_102919
Panther	1	1.100	-	-	O	PTHR19305
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3593
SonicParanoid	1	1.000	-	-		X1125
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800