Protein Alignment Snap25 and aex-4

DIOPT Version :10

• Sequence 1: NP_001036641.1
• Gene: Snap25 / 3355084
• FlyBaseID: FBgn0011288
• Length: 212
• Species: Drosophila melanogaster
• Sequence 2: NP_508641.2
• Gene: aex-4 / 188509
• WormBaseID: WBGene00006454
• Length: 234
• Species: Caenorhabditis elegans
• Alignment Length: 220
• Identity: 58/220 - (26%)
• Similarity: 112/220 - (50%)
• Gaps: 15/220 - (6%)

  Fly     5 PSEEVAPQVPKTELEELQINAQGVADESLESTRRMLALCEESKEAGIRTLVALDDQGEQLDRIEE 69
            |:||...:..|.::.:|......:..:||:|:.:|:...::.....::|..||:||.||||:||.
 Worm    16 PTEETVQKRIKLKMVDLDAEIAKLNVQSLDSSIQMIRDIDQMNVDAVQTTAALEDQDEQLDKIEA 80

  Fly    70 GMDQINADMREAEKNLSGMEKCCGIC----VLPCNKSQSFKEDDGTWKGNDDGKVVNNQPQRVMD 130
            .:..:..|:.....|::.||..|| |    :|........|.:....|.....|:.:.:.:| .:
 Worm    81 NLSNVIDDLNVVSHNITAMEHYCG-CGFFRILRAPFKYFRKRERDIIKEEVLEKMTSPKLRR-KE 143

  Fly   131 DRNGMM---------AQAGYIGRITNDAREDEMEENMGQVNTMIGNLRNMALDMGSELENQNRQI 186
            :.|.||         :...::.|:|.||.|||:|.|:.|::..:.:::|:|:||..:|:.|..::
 Worm   144 ESNMMMFTNSSKRRESTGDFMKRLTCDAIEDELERNLMQIDQGLESVKNLAVDMHVQLKLQEPKL 208

  Fly   187 DRINRKGESNEARIAVANQRAHQLL 211
            :||....|:|:..:...|.:..:||
 Worm   209 NRIEELTETNDFVVEGVNDKVKKLL 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snap25	NP_001036641.1	SNARE_SNAP25N_23N	28..87	CDD:277242	17/58 (29%)
		SNAP-25	98..150	CDD:459955	10/60 (17%)
		SNARE_SNAP25C	151..209	CDD:277238	17/57 (30%)
aex-4	NP_508641.2	PRK11281	14..>93	CDD:481316	21/76 (28%)
		SNARE	173..231	CDD:473982	17/57 (30%)