DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG41099 and MAP3K10

DIOPT Version :9

Sequence 1:NP_001015359.1 Gene:CG41099 / 3355072 FlyBaseID:FBgn0039955 Length:1124 Species:Drosophila melanogaster
Sequence 2:XP_011525283.1 Gene:MAP3K10 / 4294 HGNCID:6849 Length:962 Species:Homo sapiens


Alignment Length:212 Identity:38/212 - (17%)
Similarity:63/212 - (29%) Gaps:106/212 - (50%)


- Green bases have known domain annotations that are detailed below.


  Fly   549 CLSLKRTTLVPTLIRGGS---------------------DVNGKN-KNNLSP---LHQSIKNEDS 588
            ||:.....||....|||:                     ...|.| .:|.:|   :|:.:|:   
Human   164 CLNPPHLCLVMEYARGGALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKS--- 225

  Fly   589 DISLFLLEQGADITALTENLDSALDLSIKHDLSEVVDALCRRGIALSINKNGE----------SP 643
             |::.:||       ..||          |:|::.|..:...|:|...:|..:          :|
Human   226 -INILILE-------AIEN----------HNLADTVLKITDFGLAREWHKTTKMSAAGTYAWMAP 272

  Fly   644 --------------------LWSAL--EKGYEDVAKILVRHGI---------------------- 664
                                ||..|  |..|.::..:.|.:|:                      
Human   273 EVIRLSLFSKSSDVWSFGVLLWELLTGEVPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLE 337

  Fly   665 ------DTDCWDEGPEG 675
                  |.:|||..|.|
Human   338 GEPGPRDEECWDPDPHG 354

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG41099NP_001015359.1 BTB 67..164 CDD:279045
BTB 75..166 CDD:197585
ANK 252..385 CDD:238125
ANK repeat 291..322 CDD:293786
ANK repeat 325..362 CDD:293786
Ank_2 330..431 CDD:289560
ANK 463..595 CDD:238125 14/70 (20%)
ANK repeat 468..501 CDD:293786
Ank_2 473..572 CDD:289560 8/43 (19%)
ANK repeat 503..539 CDD:293786
ANK 536..660 CDD:238125 30/167 (18%)
ANK repeat 541..572 CDD:293786 8/43 (19%)
ANK repeat 574..637 CDD:293786 14/65 (22%)
Ank_2 579..670 CDD:289560 23/150 (15%)
ANK repeat 639..670 CDD:293786 10/90 (11%)
Ank_2 644..752 CDD:289560 13/62 (21%)
ANK repeat 672..721 CDD:293786 2/4 (50%)
ANK 721..843 CDD:238125
ANK repeat 723..752 CDD:293786
ANKYR 752..977 CDD:223738
ANK repeat 754..786 CDD:293786
ANK 820..944 CDD:238125
ANK repeat 822..855 CDD:293786
ANK repeat 857..888 CDD:293786
ANK 885..1017 CDD:238125
ANK repeat 890..921 CDD:293786
ANK repeat 923..955 CDD:293786
ANK repeat 996..1021 CDD:293786
FYVE_ANFY1 1054..1116 CDD:277267
MAP3K10XP_011525283.1 SH3_MLK1-3 20..76 CDD:212992
TyrKc 98..365 CDD:197581 38/212 (18%)
PKc_like 103..368 CDD:304357 38/212 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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