DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG41099 and Map3k11

DIOPT Version :9

Sequence 1:NP_001015359.1 Gene:CG41099 / 3355072 FlyBaseID:FBgn0039955 Length:1124 Species:Drosophila melanogaster
Sequence 2:NP_071295.2 Gene:Map3k11 / 26403 MGIID:1346880 Length:850 Species:Mus musculus


Alignment Length:530 Identity:98/530 - (18%)
Similarity:149/530 - (28%) Gaps:207/530 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   428 DRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLTALHIAALNNMPNLVKKLIVN- 491
            |...|.|.:|:.|...|              ||.|.|.|...|.|:.:    ..|||.  |::. 
Mouse   152 DEDISVTAESVRQEARL--------------FAMLAHPNIIALKAVCL----EEPNLC--LVMEY 196

  Fly   492 GASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFNCQDINGDSPLSLCLSLKRTT 556
            .|...|.....|.:...|:.|        ...|::....|.:  :|:                 .
Mouse   197 AAGGPLSRALAGRRVPPHVLV--------NWAVQIARGMHYL--HCE-----------------A 234

  Fly   557 LVPTLIRGGSDVNGKNKNNLSPL------HQSIKNEDSDISLFLLEQGADITALTENLDSALDLS 615
            |||.:.|   |:...|...|.|:      |:::|..|              ..|.........:|
Mouse   235 LVPVIHR---DLKSNNILLLQPIEGDDMEHKTLKITD--------------FGLAREWHKTTQMS 282

  Fly   616 IKHDLS----EVVDALCRRGIALSINKNGESP------LWSAL--EKGYEDVAKILVRHGID--- 665
            .....:    ||:.|        |....|...      ||..|  |..|..:..:.|.:|:.   
Mouse   283 AAGTYAWMAPEVIKA--------STFSKGSDVWSFGVLLWELLTGEVPYRGIDCLAVAYGVAVNK 339

  Fly   666 -----------------TDCWDEGPEGCRQTLLHRAID-----ENKESV-AIFLIQSQCDLDSSR 707
                             .|||.:.|        ||..|     :..|:: |..|.:...|...|.
Mouse   340 LTLPIPSTCPEPFAQLMADCWAQDP--------HRRPDFASILQQLEALEAQVLREMPRDSFHSM 396

  Fly   708 QPGPNGE------------------------GGDEAQDKASPL----HLCCHWGQTKVLQTLIDH 744
            |.|...|                        ...|.:.:|..|    ||...|            
Mouse   397 QEGWKREIQGLFDELRAKEKELLSREEELTRAAREQRSQAEQLRRREHLLAQW------------ 449

  Fly   745 GANVNLIDAESKSPLHVAIESQYDEIISILLCHPDID-------------LKLRDKSGNTPFATA 796
                         .|.|     ::..:::||...|.:             .|||.:.|....:..
Mouse   450 -------------ELEV-----FERELTLLLQQVDRERPHVRRRRGTFKRSKLRARDGGERISMP 496

  Fly   797 LDFRNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFLLAIQVDVNSRVHDANQSSP 861
            |||::....|        |:..:| |.||...:.  ..|..:.....|||::.........:.||
Mouse   497 LDFKHRITVQ--------ASPGLD-RRRNVFEVG--AGDSPTFPRFRAIQLEPTESGQTWGRQSP 550

  Fly   862 LHLAAASQNE 871
            ..|..:|..|
Mouse   551 RRLEDSSNGE 560

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG41099NP_001015359.1 BTB 67..164 CDD:279045
BTB 75..166 CDD:197585
ANK 252..385 CDD:238125
ANK repeat 291..322 CDD:293786
ANK repeat 325..362 CDD:293786
Ank_2 330..431 CDD:289560 1/2 (50%)
ANK 463..595 CDD:238125 27/138 (20%)
ANK repeat 468..501 CDD:293786 8/33 (24%)
Ank_2 473..572 CDD:289560 17/99 (17%)
ANK repeat 503..539 CDD:293786 6/35 (17%)
ANK 536..660 CDD:238125 24/141 (17%)
ANK repeat 541..572 CDD:293786 5/30 (17%)
ANK repeat 574..637 CDD:293786 11/72 (15%)
Ank_2 579..670 CDD:289560 19/128 (15%)
ANK repeat 639..670 CDD:293786 10/58 (17%)
Ank_2 644..752 CDD:289560 28/163 (17%)
ANK repeat 672..721 CDD:293786 13/78 (17%)
ANK 721..843 CDD:238125 24/138 (17%)
ANK repeat 723..752 CDD:293786 5/32 (16%)
ANKYR 752..977 CDD:223738 27/133 (20%)
ANK repeat 754..786 CDD:293786 7/44 (16%)
ANK 820..944 CDD:238125 13/52 (25%)
ANK repeat 822..855 CDD:293786 7/32 (22%)
ANK repeat 857..888 CDD:293786 5/15 (33%)
ANK 885..1017 CDD:238125
ANK repeat 890..921 CDD:293786
ANK repeat 923..955 CDD:293786
ANK repeat 996..1021 CDD:293786
FYVE_ANFY1 1054..1116 CDD:277267
Map3k11NP_071295.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 16..35
SH3_MLK1-3 46..103 CDD:212992
STKc_MLK3 114..380 CDD:271049 58/307 (19%)
Leucine-zipper 1 404..425 0/20 (0%)
Leucine-zipper 2 439..460 6/50 (12%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 535..644 6/26 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 657..850
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0192
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.