DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG41099 and ANKRD17

DIOPT Version :9

Sequence 1:NP_001015359.1 Gene:CG41099 / 3355072 FlyBaseID:FBgn0039955 Length:1124 Species:Drosophila melanogaster
Sequence 2:NP_115593.3 Gene:ANKRD17 / 26057 HGNCID:23575 Length:2603 Species:Homo sapiens


Alignment Length:1297 Identity:233/1297 - (17%)
Similarity:391/1297 - (30%) Gaps:476/1297 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   100 GNDLLSNIQQLDWSDLNEDVVLSLLRWIYTDLIDLQNDGLALDLLKAAHRFGLPSLLGICERALV 164
            |....||..:.:..|.:|:..:|.:.....|..||:|     .:|:.|.:.   .|.|..:.|.:
Human   108 GGGTSSNNSEEEEDDDDEEEEVSEVESFILDQDDLEN-----PMLETASKL---LLSGTADGADL 164

  Fly   165 TSVGVRSCIRFYCVAEEVGASTLLEYCSSIISTHWDDLTTDDFQHMSGPLLFEMLKTKTKHPLH- 228
            .:|...:..|...:.|..|..               .|:|.|.:..:.|.:...|.:.....|. 
Human   165 RTVDPETQARLEALLEAAGIG---------------KLSTADGKAFADPEVLRRLTSSVSCALDE 214

  Fly   229 --AAVRLLREDVVSLCIQKYGNSLVNTFSENGILPLEMALSSKNAKIAKSLVDNGMANINAVNME 291
              ||:..:|.:..:...|....||....||..:          || :.|.|::.  .::|....|
Human   215 AAAALTRMRAESTANAGQSDNRSLAEACSEGDV----------NA-VRKLLIEG--RSVNEHTEE 266

  Fly   292 GFSLLKSALKNGDAFSANFLLDQNCLLDLPSKPSSDTALHIICNYGPDNTPEIMEVVKKILQRQL 356
            |.|||..|...|....|..||..:..::........|.|....|.|.      :::||.:|..:.
Human   267 GESLLCLACSAGYYELAQVLLAMHANVEDRGIKGDITPLMAAANGGH------VKIVKLLLAHKA 325

  Fly   357 NINIQNIKGETPLHIAIARRNVEMVKLLLKVPNIDINLRTYDEKCALELSLSMGDH--------- 412
            ::|.|:..|.|.|..|.|...|::||:|                  ||...|:.||         
Human   326 DVNAQSSTGNTALTYACAGGYVDVVKVL------------------LESGASIEDHNENGHTPLM 372

  Fly   413 ------EFLIASILLSMGARTDRTNSKTGDSLLQVFALDRHRGEKSAIFLADFADLDHINFRGLT 471
                  ...:|.:||..||..:..:::..:|.|.:.....|. |.....|...||.:|......|
Human   373 EAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHL-EMVRFLLEAGADQEHKTDEMHT 436

  Fly   472 ALHIAALNNMPNLVKKLIVNGASSNLKHIDCGLKSALHIAVEANAIDALEAFVELKNKSHDIDFN 536
            ||..|.::....:.:.|:.:||..|:                  ..|:.|               
Human   437 ALMEACMDGHVEVARLLLDSGAQVNM------------------PADSFE--------------- 468

  Fly   537 CQDINGDSPLSLCLSLKRTTLVPTLIRGGSDVNGKNKNNLSPLHQSIKNEDSDISLFLLEQGADI 601
                   |||:|........|...||..|:.:...|....:||.::.:....::...||.|||:|
Human   469 -------SPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANI 526

  Fly   602 TALTENL-DSALDLSIKHDLSEVVDALCRRGIALSINKNGESPLWSALEKGYEDVAKILVRHGID 665
            .|.||.. ::||.|:......||.|.|.:.|..:.:..:  :||..|.::|:.::.|.|:..|.:
Human   527 NAQTEETQETALTLACCGGFLEVADFLIKAGADIELGCS--TPLMEAAQEGHLELVKYLLAAGAN 589

  Fly   666 TDCWDEGPEGCRQTLLHRAIDENKESVAIFLIQSQCDLDSSRQPGPNGEGGDEAQDKASPLHLCC 730
            .    ........|.|..|.:.....||..|:|:..||:.      ..|||      .:||....
Human   590 V----HATTATGDTALTYACENGHTDVADVLLQAGADLEH------ESEGG------RTPLMKAA 638

  Fly   731 HWGQTKVLQTLIDHGANVNLIDAES-KSPLHVAIESQYDEIISILLCH-PDIDLKLRD------- 786
            ..|....:|.||..|||||...|.: .:.|.:|....:..::.:||.| .|...:|:|       
Human   639 RAGHVCTVQFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIE 703

  Fly   787 --KSGNTP--------------------------------------------------------F 793
              |.|:|.                                                        .
Human   704 AAKGGHTSVVCYLLDYPNNLLSAPPPDVTQLTPPSHDLNRAPRVPVQALPMVVPPQEPDKPPANV 768

  Fly   794 ATALDFRNHNAA----------------------------------------------------- 805
            ||.|..||..|:                                                     
Human   769 ATTLPIRNKAASKQKSSSHLPANSQDVQGYITNQSPESIVEEAQGKLTELEQRIKEAIEKNAQLQ 833

  Fly   806 -----------------------------QRILDRFPTAAEQMDIRGRNFL-------------- 827
                                         |:||:.......::.::.:..|              
Human   834 SLELAHADQLTKEKIEELNKTREEQIQKKQKILEELQKVERELQLKTQQQLKKQYLEVKAQRIQL 898

  Fly   828 ---------HLAI---------------------------------------------------- 831
                     ||.:                                                    
Human   899 QQQQQQSCQHLGLLTPVGVGEQLSEGDYARLQQVDPVLLKDEPQQTAAQMGFAPIQPLAMPQALP 963

  Fly   832 -------------------------------------------------------LKDDLESVLF 841
                                                                   |.|.|:.::.
Human   964 LAAGPLPPGSIANLTELQGVIVGQPVLGQAQLAGLGQGILTETQQGLMVASPAQTLNDTLDDIMA 1028

  Fly   842 LL-----------------------------------------AIQVDVNSRVHDANQSSPLHLA 865
            .:                                         ||.:|..:   ::|..:.|.||
Human  1029 AVSGRASAMSNTPTHSIAASISQPQTPTPSPIISPSAMLPIYPAIDIDAQT---ESNHDTALTLA 1090

  Fly   866 AASQNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDA-TDADGNNALH 929
            .|..:|.:.:.|:..||.:..||.....||.:|...|::..|..|:.|.||.:| ::...:..|.
Human  1091 CAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEAQSERTKDTPLS 1155

  Fly   930 IAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHELCRVVEDSTAGL--ICELFLESMPKYPINI 992
            :|....:..:| |||.....|.|..|:....||...      ::.|.  |.::.|.:..:.....
Human  1156 LACSGGRQEVV-ELLLARGANKEHRNVSDYTPLSLA------ASGGYVNIIKILLNAGAEINSRT 1213

  Fly   993 PDMDGNTPLLLSFMRGQSPLCKILVKAG----ACLGTENKDGINIFNFKLATDQLLHNLLDQ 1050
            ....|.:||:|:.|.|.:...|:|:..|    |.:.|.....:.:..|:..| :::..|||:
Human  1214 GSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQGRT-EVVSLLLDR 1274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG41099NP_001015359.1 BTB 67..164 CDD:279045 15/63 (24%)
BTB 75..166 CDD:197585 15/65 (23%)
ANK 252..385 CDD:238125 34/132 (26%)
ANK repeat 291..322 CDD:293786 10/30 (33%)
ANK repeat 325..362 CDD:293786 8/36 (22%)
Ank_2 330..431 CDD:289560 27/115 (23%)
ANK 463..595 CDD:238125 22/131 (17%)
ANK repeat 468..501 CDD:293786 8/32 (25%)
Ank_2 473..572 CDD:289560 16/98 (16%)
ANK repeat 503..539 CDD:293786 2/35 (6%)
ANK 536..660 CDD:238125 33/124 (27%)
ANK repeat 541..572 CDD:293786 8/30 (27%)
ANK repeat 574..637 CDD:293786 19/63 (30%)
Ank_2 579..670 CDD:289560 25/91 (27%)
ANK repeat 639..670 CDD:293786 7/30 (23%)
Ank_2 644..752 CDD:289560 29/107 (27%)
ANK repeat 672..721 CDD:293786 12/48 (25%)
ANK 721..843 CDD:238125 38/400 (10%)
ANK repeat 723..752 CDD:293786 11/28 (39%)
ANKYR 752..977 CDD:223738 63/547 (12%)
ANK repeat 754..786 CDD:293786 7/33 (21%)
ANK 820..944 CDD:238125 34/295 (12%)
ANK repeat 822..855 CDD:293786 9/203 (4%)
ANK repeat 857..888 CDD:293786 9/30 (30%)
ANK 885..1017 CDD:238125 33/134 (25%)
ANK repeat 890..921 CDD:293786 10/31 (32%)
ANK repeat 923..955 CDD:293786 8/31 (26%)
ANK repeat 996..1021 CDD:293786 9/28 (32%)
FYVE_ANFY1 1054..1116 CDD:277267
ANKRD17NP_115593.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..143 8/34 (24%)
ANK 1 233..262 8/41 (20%)
Ank_2 238..330 CDD:289560 26/110 (24%)
ANK repeat 238..264 CDD:293786 8/38 (21%)
ANK 261..387 CDD:238125 35/149 (23%)
ANK repeat 266..298 CDD:293786 10/31 (32%)
ANK 2 266..295 10/28 (36%)
ANK 3 300..329 7/34 (21%)
ANK repeat 303..331 CDD:293786 8/33 (24%)
Ank_2 305..394 CDD:289560 27/112 (24%)
ANK 328..454 CDD:238125 33/144 (23%)
ANK repeat 333..364 CDD:293786 13/48 (27%)
ANK 4 333..362 12/46 (26%)
ANK 5 366..395 5/28 (18%)
ANK repeat 366..394 CDD:293786 5/27 (19%)
ANK 396..520 CDD:238125 29/164 (18%)
ANK repeat 400..431 CDD:293786 8/31 (26%)
ANK 6 400..429 7/29 (24%)
Ank_4 403..454 CDD:290365 12/51 (24%)
ANK 7 433..462 7/28 (25%)
ANK repeat 435..464 CDD:293786 8/46 (17%)
Ank_2 438..529 CDD:289560 25/130 (19%)
ANK repeat 466..497 CDD:293786 9/52 (17%)
ANK 8 466..495 9/50 (18%)
ANK repeat 499..529 CDD:293786 8/29 (28%)
ANK 9 499..528 8/28 (29%)
ANK repeat 532..561 CDD:293786 8/28 (29%)
ANK 10 533..562 8/28 (29%)
Ank_4 536..584 CDD:290365 13/49 (27%)
ANK 11 563..592 7/34 (21%)
ANK 566..684 CDD:238125 33/133 (25%)
ANK repeat 566..594 CDD:293786 7/31 (23%)
Ank_2 568..659 CDD:289560 29/106 (27%)
ANK repeat 596..627 CDD:293786 9/36 (25%)
ANK 12 596..625 9/28 (32%)
ANK repeat 629..658 CDD:293786 12/34 (35%)
ANK 13 629..658 12/34 (35%)
Ank_2 634..723 CDD:289560 22/88 (25%)
ANK 662..>723 CDD:238125 11/60 (18%)
ANK repeat 663..693 CDD:293786 6/29 (21%)
ANK 14 663..692 6/28 (21%)
ANK 15 696..725 4/28 (14%)
OmpH 794..>893 CDD:281871 4/98 (4%)
AhaH 805..881 CDD:131972 3/75 (4%)
ANKYR 1046..1272 CDD:223738 51/236 (22%)
ANK 16 1082..1111 9/28 (32%)
ANK 1082..1110 CDD:197603 9/27 (33%)
ANK repeat 1084..1113 CDD:293786 8/28 (29%)
ANK 1111..1238 CDD:238125 33/133 (25%)
ANK repeat 1115..1147 CDD:293786 10/31 (32%)
ANK 17 1115..1144 9/28 (32%)
ANK repeat 1149..1180 CDD:293786 8/31 (26%)
ANK 18 1149..1178 7/29 (24%)
ANK repeat 1182..1213 CDD:293786 5/36 (14%)
ANK 19 1182..1211 5/34 (15%)
ANK repeat 1217..1247 CDD:293786 9/29 (31%)
ANK 20 1217..1246 9/28 (32%)
ANK repeat 1250..1282 CDD:293786 6/26 (23%)
ANK 21 1251..1280 5/25 (20%)
ANK 1280..1406 CDD:238125
ANK repeat 1284..1313 CDD:293786
ANK 22 1284..1313
Ank_2 1289..1383 CDD:289560
ANK 23 1319..1348
ANK repeat 1321..1350 CDD:293786
ANK repeat 1352..1383 CDD:293786
ANK 24 1352..1381
ANK 25 1385..1414
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1479..1500
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1517..1717
NusA <1720..1767 CDD:223273
KH-I 1727..1789 CDD:238053
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1906..1995
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2011..2192
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2273..2332
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 2381..2423
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1115202at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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