DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG41099 and si:ch1073-398c20.3

DIOPT Version :9

Sequence 1:	NP_001015359.1	Gene:	CG41099 / 3355072	FlyBaseID:	FBgn0039955	Length:	1124	Species:	Drosophila melanogaster
Sequence 2:	XP_021331002.1	Gene:	si:ch1073-398c20.3 / 100331458	ZFINID:	ZDB-GENE-161017-19	Length:	418	Species:	Danio rerio

Alignment Length:	137	Identity:	36/137 - (26%)
Similarity:	48/137 - (35%)	Gaps:	43/137 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1004 SFMRGQSPLCKILVKAGACLGTENKDGINI-------FNFKLATDQLLHNLLDQLPQESPWAESD 1061
            ||.|.||        ....:.|.|::..:|       |.:|.:.::.:.|...    |.|:.
Zfish   223 SFTRKQS--------LDVHMRTHNEERPHICQECGVSFIYKNSLEEHMRNHTG----EKPFT--- 272

  Fly  1062 YCQHCTNRFTITM------------RKHHCRHCGRVLCSKCSCNDVPILKFGINKPVRVCTVCFN 1114
             ||||.|.||...            |.|.|:.||.....|.|..:......| .||       |.
Zfish   273 -CQHCGNGFTRKRNLEDHMRIHNEERPHICQECGVSFIYKNSLTEHMTTHTG-EKP-------FT 328

  Fly  1115 VLQCGNG 1121
            ..|||||
Zfish   329 CQQCGNG 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG41099	NP_001015359.1	BTB	67..164	CDD:279045
		BTB	75..166	CDD:197585
		ANK	252..385	CDD:238125
		ANK repeat	291..322	CDD:293786
		ANK repeat	325..362	CDD:293786
		Ank_2	330..431	CDD:289560
		ANK	463..595	CDD:238125
		ANK repeat	468..501	CDD:293786
		Ank_2	473..572	CDD:289560
		ANK repeat	503..539	CDD:293786
		ANK	536..660	CDD:238125
		ANK repeat	541..572	CDD:293786
		ANK repeat	574..637	CDD:293786
		Ank_2	579..670	CDD:289560
		ANK repeat	639..670	CDD:293786
		Ank_2	644..752	CDD:289560
		ANK repeat	672..721	CDD:293786
		ANK	721..843	CDD:238125
		ANK repeat	723..752	CDD:293786
		ANKYR	752..977	CDD:223738
		ANK repeat	754..786	CDD:293786
		ANK	820..944	CDD:238125
		ANK repeat	822..855	CDD:293786
		ANK repeat	857..888	CDD:293786
		ANK	885..1017	CDD:238125	5/12 (42%)
		ANK repeat	890..921	CDD:293786
		ANK repeat	923..955	CDD:293786
		ANK repeat	996..1021	CDD:293786	5/16 (31%)
		FYVE_ANFY1	1054..1116	CDD:277267	20/73 (27%)
si:ch1073-398c20.3	XP_021331002.1	C2H2 Zn finger	77..97	CDD:275368
		COG5048	90..411	CDD:227381	36/137 (26%)
		C2H2 Zn finger	105..125	CDD:275368
		C2H2 Zn finger	133..153	CDD:275368
		C2H2 Zn finger	161..181	CDD:275368
		C2H2 Zn finger	189..209	CDD:275368
		C2H2 Zn finger	217..237	CDD:275368	5/21 (24%)
		C2H2 Zn finger	245..265	CDD:275368	2/19 (11%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		C2H2 Zn finger	301..321	CDD:275368	5/19 (26%)
		C2H2 Zn finger	329..349	CDD:275368	5/7 (71%)
		C2H2 Zn finger	357..377	CDD:275368
		C2H2 Zn finger	385..405	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1115202at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010